{"id":"W2064754526","doi":"10.1089/vim.2009.0054","title":"Disparate Regulation of LPS-Induced MAPK Signaling and IL-12p40 Expression Between Different Myeloid Cell Types with and without HIV Infection","year":2010,"lang":"en","type":"article","venue":"Viral Immunology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; Children's Hospital of Eastern Ontario; University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"p38 mitogen-activated protein kinases; Transcription factor; Sp1 transcription factor; Biology; MAPK/ERK pathway; Molecular biology; Cell biology; Monocyte; Cell culture; Promoter; Signal transduction; Gene expression; Immunology; Gene; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001977205,0.000206221,0.0003165329,0.0003367157,0.0002146394,0.0004931128,0.0001591432,0.0002413276,0.001203603],"category_scores_gemma":[0.000288506,0.0001841456,0.0002457485,0.0002729854,0.0002795503,0.0002186532,0.0002587099,0.000524157,0.0002545218],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002017071,"about_ca_system_score_gemma":0.0001727214,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002885932,"about_ca_topic_score_gemma":0.0003041481,"domain_scores_codex":[0.9995418,0.00009084826,0.00005734079,0.00007830856,0.0000899123,0.0001417991],"domain_scores_gemma":[0.9998363,0.00004712363,0.00003028248,0.00002291313,0.00002853285,0.00003486592],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004322097,0.00003870796,0.0009922958,0.0000365466,0.000006800202,0.00007599298,0.00005307498,0.00002152625,0.9970874,0.00005855763,0.00001567842,0.001181174],"study_design_scores_gemma":[0.00003869205,0.0008264682,0.05641041,0.0000183311,0.00006081741,0.00117407,0.0002616763,0.0007498401,0.9384313,0.000135259,0.001877529,0.00001560811],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974269,0.0009906029,0.0008441603,0.00002272665,0.00001562717,0.00002723079,0.0002617597,0.0000142795,0.0003967363],"genre_scores_gemma":[0.9955266,0.001083112,0.001661564,0.00004121958,0.00001936518,0.0000990681,0.0007577853,0.000008659291,0.0008025718],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001203603,"threshold_uncertainty_score":0.004026413,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007815279779781276,"score_gpt":0.2172468528851688,"score_spread":0.2094315731053875,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}