{"id":"W2064756027","doi":"10.1016/j.cmet.2007.01.009","title":"BMP4-BMPR1A Signaling in β Cells Is Required for and Augments Glucose-Stimulated Insulin Secretion","year":2007,"lang":"en","type":"article","venue":"Cell Metabolism","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":128,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Bayer Canada; Leonard M. Miller School of Medicine; Vetenskapsrådet","keywords":"Proinsulin; Internal medicine; Endocrinology; Biology; Insulin; Secretion; Incretin; Signal transduction; Transgene; Insulin receptor; Cell biology; Type 2 diabetes; Diabetes mellitus; Insulin resistance; Medicine; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003211137,0.0005895245,0.0005018029,0.0007318771,0.0003618489,0.001000759,0.000448793,0.000433929,0.00311343],"category_scores_gemma":[0.0003117016,0.0005453133,0.0005476755,0.0002853389,0.0006007385,0.0004651727,0.0006688556,0.001845074,0.001140745],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008312961,"about_ca_system_score_gemma":0.0005428086,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001150034,"about_ca_topic_score_gemma":0.00135532,"domain_scores_codex":[0.9995454,0.0000812158,0.00004294884,0.00005539789,0.0001515058,0.0001235423],"domain_scores_gemma":[0.9996718,0.00005136082,0.00007236216,0.00004238438,0.00003385839,0.0001283281],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002719361,0.00002140963,0.00022368,0.00002449818,0.000005901252,0.00007320198,0.000007780551,0.00004854476,0.9982128,0.0002433712,0.00006900793,0.0007978659],"study_design_scores_gemma":[0.00004032348,0.00008534144,0.004884547,0.000007905897,0.00001945039,0.0003386246,0.00006848497,0.0006975573,0.9903532,0.0001628527,0.003336444,0.000005132611],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.985925,0.00337323,0.003742247,0.0007128039,0.0001415117,0.00003857076,0.0009107407,0.00018802,0.004967885],"genre_scores_gemma":[0.9853436,0.001157859,0.004010241,0.0002196594,0.00004476491,0.0000516075,0.001471557,0.0001428092,0.007557989],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00311343,"threshold_uncertainty_score":0.01041543,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02029041912013948,"score_gpt":0.2671113005472193,"score_spread":0.2468208814270798,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}