{"id":"W2064807159","doi":"10.1517/14740338.2012.705828","title":"Anticonvulsant hypersensitivity syndrome: an update","year":2012,"lang":"en","type":"review","venue":"Expert Opinion on Drug Safety","topic":"Drug-Induced Adverse Reactions","field":"Medicine","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital; Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Medicine; Lamotrigine; Anticonvulsant; Carbamazepine; Phenobarbital; Phenytoin; Pharmacovigilance; Incidence (geometry); Genetic testing; Drug; Pharmacology; Intensive care medicine; Epilepsy; Internal medicine; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0007092298,0.0009904553,0.002944496,0.0005241479,0.0002881261,0.0000397028,0.0002740296,0.0005868891,0.0001381074],"category_scores_gemma":[0.0001064364,0.0007945946,0.0009764479,0.0005139073,0.0001522952,0.0003874929,0.0001492242,0.001372276,0.003327808],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008046979,"about_ca_system_score_gemma":0.0005769845,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007289088,"about_ca_topic_score_gemma":0.000003466422,"domain_scores_codex":[0.9957831,0.0006192148,0.0009983701,0.001039475,0.000711048,0.0008487897],"domain_scores_gemma":[0.9963958,0.000318083,0.000484311,0.00183743,0.0001121351,0.0008522042],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001521547,0.0007957949,9.818946e-7,0.00155062,0.0002862207,0.0001692792,0.000160908,4.514732e-7,0.000004751857,0.0006872729,0.0004324268,0.9958961],"study_design_scores_gemma":[0.0006323613,0.0000503418,0.0001503078,0.01034836,0.0002669306,0.004053575,0.0001679648,0.00001018578,0.000006598919,0.000003060262,0.9835417,0.0007685773],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001262958,0.9757083,0.0000219139,0.0006563205,0.005078669,0.00161302,0.0001673531,0.0004049846,0.01633679],"genre_scores_gemma":[0.0009374152,0.9935846,0.0003196069,0.0005547765,0.001689831,0.0001002403,0.001904654,0.0002468952,0.0006620198],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9951275,"threshold_uncertainty_score":0.9994505,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09170839139657168,"score_gpt":0.3903947745040657,"score_spread":0.2986863831074941,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}