{"id":"W2064933387","doi":"10.1210/me.2014-1183","title":"Regulation of Human Growth Hormone Receptor Expression by MicroRNAs","year":2014,"lang":"en","type":"article","venue":"Molecular Endocrinology","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; Montreal Children's Hospital","funders":"Canadian Institutes of Health Research; Fonds de Recherche du Québec - Santé; National Institute for Health and Care Research; National Institutes of Health; McGill University Health Centre","keywords":"Biology; Growth hormone receptor; microRNA; HEK 293 cells; Three prime untranslated region; Untranslated region; Regulation of gene expression; Gene expression; Luciferase; In silico; Genetics; Cell biology; Cancer research; Gene; Molecular biology; Transfection; Messenger RNA; Endocrinology; Growth hormone","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002730437,0.0002968523,0.0003537158,0.0002278977,0.0002123157,0.0004301569,0.0001721369,0.0002089861,0.0008529368],"category_scores_gemma":[0.0003293542,0.000258388,0.0004895187,0.0001592078,0.0001677645,0.0001631743,0.0001512968,0.0003051898,0.0006383762],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002934562,"about_ca_system_score_gemma":0.000281819,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006733458,"about_ca_topic_score_gemma":0.0008009113,"domain_scores_codex":[0.9995881,0.00007920176,0.00003424562,0.0001213624,0.0001267835,0.00005039577],"domain_scores_gemma":[0.9999079,0.00003509042,0.00002191655,0.000008794812,0.00001730712,0.000009014441],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002177864,0.00001721432,0.0007680497,0.00009523988,0.00001727436,0.0001206257,0.00003147989,0.0003145056,0.9923558,0.0001701921,0.0001984913,0.005693396],"study_design_scores_gemma":[0.00004827635,0.0002960544,0.01070961,0.00001912325,0.00004966258,0.0005910122,0.00004333122,0.007039085,0.968163,0.0001496852,0.0128686,0.00002267979],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9387319,0.01388572,0.03659337,0.0003390864,0.0002672285,0.0002144385,0.002292003,0.0008987981,0.006777448],"genre_scores_gemma":[0.9609646,0.003291281,0.03015314,0.0002017422,0.00003811274,0.0001307334,0.002055116,0.00009563137,0.003069598],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008529368,"threshold_uncertainty_score":0.002853394,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005368236688072248,"score_gpt":0.2293708370934694,"score_spread":0.2240026004053972,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}