{"id":"W2064933387","doi":"10.1210/me.2014-1183","title":"Regulation of Human Growth Hormone Receptor Expression by MicroRNAs","year":2014,"lang":"en","type":"article","venue":"Molecular Endocrinology","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; Montreal Children's Hospital","funders":"Canadian Institutes of Health Research; Fonds de Recherche du Québec - Santé; National Institute for Health and Care Research; National Institutes of Health; McGill University Health Centre","keywords":"Biology; Growth hormone receptor; microRNA; HEK 293 cells; Three prime untranslated region; Untranslated region; Regulation of gene expression; Gene expression; Luciferase; In silico; Genetics; Cell biology; Cancer research; Gene; Molecular biology; Transfection; Messenger RNA; Endocrinology; Growth hormone","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008880853,0.0001852113,0.0002023153,0.00007843292,0.00006508415,0.00000838715,0.0002280651,0.0001778399,0.00004743187],"category_scores_gemma":[0.00009382068,0.0001979117,0.0001117663,0.0000818599,0.0001416758,0.000004838054,0.0001418649,0.00007723479,0.00001706357],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000018392,"about_ca_system_score_gemma":0.00001885135,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001655975,"about_ca_topic_score_gemma":0.000001400993,"domain_scores_codex":[0.9986297,0.0001970489,0.0003128589,0.0004187584,0.0001372638,0.0003043641],"domain_scores_gemma":[0.99909,0.000008736291,0.0001973547,0.0004957596,0.0001320729,0.0000761067],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005942015,0.00006951,0.0005098895,0.00001925485,0.00003184053,9.096534e-7,0.000009873374,0.00001287592,0.9864607,0.001357388,0.01099514,0.0004732452],"study_design_scores_gemma":[0.0007636998,0.000300322,0.004155979,0.00001048212,0.0000194897,0.00001160248,0.000005840816,0.0000143859,0.981109,0.0005670181,0.01285351,0.0001886643],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.981851,0.001433163,0.0153854,0.000141223,0.00007815169,0.0001907864,0.0000190508,0.00002626739,0.0008749857],"genre_scores_gemma":[0.9973637,0.00004410625,0.001395081,0.0001186112,0.00008138969,0.00002456788,0.0007024592,0.00003796921,0.0002320722],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01551277,"threshold_uncertainty_score":0.8070605,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005368236688072248,"score_gpt":0.2293708370934694,"score_spread":0.2240026004053972,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}