{"id":"W2065020908","doi":"10.1002/cbic.201200493","title":"Two Synthetic Antibodies that Recognize and Neutralize Distinct Proteolytic Forms of the Ebola Virus Envelope Glycoprotein","year":2012,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institute of General Medical Sciences; U.S. Public Health Service","keywords":"Ebola virus; Filoviridae; Viral envelope; Epitope; Viral entry; Glycoprotein; Antibody; Proteases; Virology; Proteolysis; Lipid bilayer fusion; Chemistry; Endosome; Biology; Virus; Biochemistry; Viral replication; Cell; Paramyxoviridae; Enzyme; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003153246,0.000167813,0.0002811871,0.00005514697,0.000135467,0.00002187941,0.000101013,0.00008623111,0.0001375724],"category_scores_gemma":[0.0001882491,0.00009852385,0.000116402,0.0002046499,0.0003173375,0.0001075154,0.000164929,0.0002407599,0.00002723693],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004386285,"about_ca_system_score_gemma":0.00005543272,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001636316,"about_ca_topic_score_gemma":0.00001629698,"domain_scores_codex":[0.9989423,0.00003174278,0.0002035994,0.0001955005,0.0002407146,0.0003862012],"domain_scores_gemma":[0.999285,0.0000491582,0.00008648029,0.0003448623,0.00007714592,0.0001573088],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001721111,0.0002899632,0.07369643,0.0005867432,0.00009586898,0.000003407197,0.000430959,7.323187e-8,0.9097244,0.0003711205,0.0002373297,0.01439156],"study_design_scores_gemma":[0.0007615492,0.0000776827,0.07344476,0.0002121244,0.00006360234,0.000116467,0.0001186953,0.00001421156,0.9239634,0.000138396,0.0009729941,0.0001161178],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9879556,0.0009295244,0.00002438501,0.0004582013,0.00008407751,0.0008209697,0.00001129407,0.00003296377,0.009682952],"genre_scores_gemma":[0.9976043,0.00009394081,0.0001931919,0.00006680239,0.0001032361,0.00007391323,0.00000559932,0.00002459327,0.001834461],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01427544,"threshold_uncertainty_score":0.4017686,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03599692101445832,"score_gpt":0.3098694211088102,"score_spread":0.2738725000943519,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}