{"id":"W2065022745","doi":"10.1021/bi992232k","title":"Active Site Residues of <i>cis</i>-2,3-Dihydro-2,3-dihydroxybiphenyl Dehydrogenase from <i>Comamonas testosteroni</i> Strain B-356","year":2000,"lang":"en","type":"article","venue":"Biochemistry","topic":"Microbial bioremediation and biosurfactants","field":"Environmental Science","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University; Institut National de la Recherche Scientifique","funders":"","keywords":"Comamonas testosteroni; Stereochemistry; Dehydrogenase; Chemistry; Enzyme; NAD+ kinase; Active site; Residue (chemistry); Biphenyl; Catalytic triad; Biochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009061521,0.0003762781,0.0002454757,0.0001119292,0.0001069765,0.0002634583,0.0003354459,0.000276066,0.0006726307],"category_scores_gemma":[0.000176959,0.0001682137,0.0003295047,0.000214312,0.0001538676,0.0001728995,0.0001538774,0.000393888,0.0004505964],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005640411,"about_ca_system_score_gemma":0.0002406218,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002715614,"about_ca_topic_score_gemma":0.00192769,"domain_scores_codex":[0.9998647,0.00001901949,0.00001857061,0.00002827389,0.00005191866,0.00001747153],"domain_scores_gemma":[0.999868,0.00001711308,0.00004505125,0.00001475182,0.00001974245,0.00003525277],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001444267,0.00002411185,0.0004401129,0.00002670621,0.000005587824,0.00005008313,0.00001505754,0.00009873768,0.9985254,0.00004148704,0.00001878759,0.0006095317],"study_design_scores_gemma":[0.00001921797,0.0001323521,0.007763124,0.000005679555,0.0000170665,0.0002834127,0.00004387927,0.0008025567,0.9897461,0.00002273922,0.001154531,0.000009202594],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975782,0.000245586,0.001198771,0.00004382511,0.00001169971,0.00001037063,0.0004941021,0.00003293207,0.000384592],"genre_scores_gemma":[0.9942292,0.0002231429,0.001859234,0.00003584707,0.000003919496,0.00000907559,0.00267907,0.000032088,0.0009284567],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002715614,"threshold_uncertainty_score":0.005399585,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004605730193746892,"score_gpt":0.1894865388564363,"score_spread":0.1848808086626895,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}