{"id":"W2065073682","doi":"10.1097/fpc.0b013e328344c5c6","title":"Bioavailability of testosterone enanthate dependent on genetic variation in the phosphodiesterase 7B but not on the uridine 5′-diphospho-glucuronosyltransferase (UGT2B17) gene.","year":2011,"lang":"en","type":"article","venue":"Pharmacogenetics and Genomics","topic":"Hormonal and reproductive studies","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Stockholms Läns Landsting; Canadian Institutes of Health Research; World Anti-Doping Agency; Canada Research Chairs","keywords":"Androgen; Testosterone (patch); Endocrinology; Internal medicine; Glucuronosyltransferase; Biology; Genetic variation; Allele; Genotype; Single-nucleotide polymorphism; Gene; Chemistry; Genetics; Medicine; Hormone; Microsome; In vitro","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002931145,0.0002422661,0.0002900203,0.0002397756,0.0001289123,0.0002822501,0.000145372,0.0002696948,0.002698536],"category_scores_gemma":[0.0006697592,0.0002172888,0.0003365987,0.0001920599,0.0003078475,0.0001227229,0.0001291447,0.0003045337,0.0003024089],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001521295,"about_ca_system_score_gemma":0.0001204538,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009850271,"about_ca_topic_score_gemma":0.0007080947,"domain_scores_codex":[0.9996327,0.0001525136,0.00001845227,0.000101744,0.00006440978,0.00003003531],"domain_scores_gemma":[0.9994501,0.0001950034,0.0001829806,0.00006044375,0.00002777793,0.00008366915],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.007785734,0.0004471118,0.3089302,0.000121042,0.0007922068,0.001104084,0.0003895853,0.0002300703,0.6648425,0.0002352999,0.000364866,0.01475727],"study_design_scores_gemma":[0.0000843142,0.0008284946,0.979353,0.00000840647,0.0001609003,0.001662628,0.00006438366,0.0004898182,0.01660129,0.00008627276,0.0006517958,0.000008732564],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976224,0.0008778619,0.0007388402,0.00005015594,0.00001885571,0.0000126568,0.0001775082,0.000008902086,0.0004926947],"genre_scores_gemma":[0.9989248,0.0001127173,0.0002141127,0.00002502108,0.000007677065,0.000006564462,0.0001467583,0.00001135456,0.0005511012],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002698536,"threshold_uncertainty_score":0.009027541,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05571974258801401,"score_gpt":0.2605048108894198,"score_spread":0.2047850683014058,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}