{"id":"W2065073682","doi":"10.1097/fpc.0b013e328344c5c6","title":"Bioavailability of testosterone enanthate dependent on genetic variation in the phosphodiesterase 7B but not on the uridine 5′-diphospho-glucuronosyltransferase (UGT2B17) gene.","year":2011,"lang":"en","type":"article","venue":"Pharmacogenetics and Genomics","topic":"Hormonal and reproductive studies","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Stockholms Läns Landsting; Canadian Institutes of Health Research; World Anti-Doping Agency; Canada Research Chairs","keywords":"Androgen; Testosterone (patch); Endocrinology; Internal medicine; Glucuronosyltransferase; Biology; Genetic variation; Allele; Genotype; Single-nucleotide polymorphism; Gene; Chemistry; Genetics; Medicine; Hormone; Microsome; In vitro","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006100694,0.0002602186,0.0003157852,0.00006708071,0.0001429148,0.00001349314,0.0001788247,0.00005290912,0.0000484228],"category_scores_gemma":[0.00005887546,0.0001446771,0.00008191785,0.0001326798,0.0002466842,0.00001816185,0.00006548437,0.000234745,0.00001377954],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004740633,"about_ca_system_score_gemma":0.0000582102,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001884291,"about_ca_topic_score_gemma":0.0000220551,"domain_scores_codex":[0.9984463,0.0001310053,0.0004257906,0.0004551791,0.0002693198,0.0002724286],"domain_scores_gemma":[0.9990813,0.0001843289,0.0001096535,0.0004484923,0.0001053933,0.0000708278],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003506178,0.00192383,0.02643454,0.0001533484,0.0003915695,0.00008691211,0.0141038,0.0002332394,0.9318852,0.000305032,0.00005526722,0.02092105],"study_design_scores_gemma":[0.001277153,0.0008509615,0.3615812,0.00002293034,0.0002097202,0.00002370997,0.000317662,0.0002045956,0.6346558,0.0002076297,0.0004832089,0.000165395],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942262,0.002951047,0.00006179503,0.001175959,0.000174836,0.000928251,0.0001066644,0.000009387199,0.0003658323],"genre_scores_gemma":[0.992544,0.005870415,0.0002995903,0.001051105,0.0001076715,0.00005419944,0.000006052502,0.00002327721,0.00004368806],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3351467,"threshold_uncertainty_score":0.5899761,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05571974258801401,"score_gpt":0.2605048108894198,"score_spread":0.2047850683014058,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}