{"id":"W2065093310","doi":"10.1007/s00262-005-0698-x","title":"Virulizin, a novel immunotherapy agent, activates NK cells through induction of IL-12 expression in macrophages","year":2005,"lang":"en","type":"article","venue":"Cancer Immunology Immunotherapy","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"","keywords":"Cytotoxic T cell; Interleukin 12; Cancer research; Cytotoxicity; Macrophage; Melanoma; Antibody; Immunology; Immunotherapy; Cancer immunotherapy; Biology; Chemistry; Immune system; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001302735,0.0002399581,0.0003079705,0.0001798456,0.0001175096,0.0002831465,0.0001201526,0.0002247738,0.0007251329],"category_scores_gemma":[0.00008208862,0.0001079802,0.0001976226,0.0001009564,0.0001924872,0.0001940025,0.0001635101,0.0006580831,0.0001957062],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002145477,"about_ca_system_score_gemma":0.0002224611,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001604601,"about_ca_topic_score_gemma":0.0003379546,"domain_scores_codex":[0.9998969,0.00002469712,0.000006123737,0.00001177278,0.00002122189,0.00003928822],"domain_scores_gemma":[0.9999651,0.0000100709,0.000007496782,0.000005231228,0.000003433348,0.000008716057],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008468351,0.0001012884,0.0003139971,0.00004987363,0.000007750845,0.00009682076,0.00001815671,0.0001492012,0.9894673,0.0002368514,0.0001188308,0.008593074],"study_design_scores_gemma":[0.0002709068,0.001612806,0.005134553,0.000007702556,0.00004053243,0.0005489129,0.00003035128,0.001043981,0.9873793,0.0002001935,0.003724894,0.000005975643],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922243,0.003196703,0.002573173,0.000170328,0.00007200357,0.00003134667,0.00008641484,0.00006454617,0.001581065],"genre_scores_gemma":[0.9955174,0.001358115,0.001131933,0.00005317685,0.00003750779,0.00003195226,0.0001035456,0.000006751283,0.001759554],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007251329,"threshold_uncertainty_score":0.00242579,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02276334240597446,"score_gpt":0.2807844999294116,"score_spread":0.2580211575234372,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}