{"id":"W2065115599","doi":"10.1016/j.biomaterials.2011.03.015","title":"Antitumor activity of liposomal ErbB2/HER2 epitope peptide-based vaccine constructs incorporating TLR agonists and mannose receptor targeting","year":2011,"lang":"en","type":"article","venue":"Biomaterials","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":79,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Institute of Cancer Research; Institut National Du Cancer; Ligue Contre le Cancer","keywords":"Epitope; Peptide vaccine; Peptide; Liposome; Mannose; Mannose receptor; Receptor; Materials science; Cancer research; Medicine; Immunology; Biology; Biochemistry; Antibody; Nanotechnology; In vitro","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002467073,0.0003422071,0.0002226653,0.0001574882,0.00009386881,0.0002567821,0.0001685698,0.0003451408,0.00120772],"category_scores_gemma":[0.0001928408,0.0001362764,0.0001498687,0.000134072,0.0001842931,0.0003069189,0.0001808042,0.000522008,0.0002565846],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002209665,"about_ca_system_score_gemma":0.0002378019,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004298683,"about_ca_topic_score_gemma":0.0003577638,"domain_scores_codex":[0.9998616,0.00003294371,0.00001014857,0.00001930001,0.0000284443,0.00004752334],"domain_scores_gemma":[0.9999143,0.00003173049,0.00001603444,0.00001105052,0.00001163834,0.00001517986],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006131466,0.0001432982,0.0001053945,0.00005109533,0.00000787265,0.00002809245,0.00001691135,0.0006046637,0.9959385,0.0001576072,0.00006218933,0.002271323],"study_design_scores_gemma":[0.00008004146,0.001258839,0.0005370149,0.000005038607,0.00002350579,0.00007622787,0.00001551803,0.001880243,0.9952407,0.00003907898,0.0008399525,0.000003783926],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973657,0.0007244541,0.001023173,0.00004469807,0.00002819889,0.00001702734,0.00007267282,0.00002376594,0.0007003947],"genre_scores_gemma":[0.9980721,0.000338179,0.0005553091,0.00002298987,0.000007622659,0.00001618121,0.0001353399,0.000006601425,0.000845585],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00120772,"threshold_uncertainty_score":0.004040182,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01805359988871685,"score_gpt":0.232797847918359,"score_spread":0.2147442480296421,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}