{"id":"W2065162032","doi":"10.1073/pnas.0937287100","title":"Iron chelators modulate the fusogenic properties of <i>Salmonella</i> -containing phagosomes","year":2003,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Iron Metabolism and Disorders","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; SickKids Foundation; Hospital for Sick Children","funders":"Canadian Institutes of Health Research; U.S. Public Health Service; National Institutes of Health","keywords":"Phagosome; Endosome; Intracellular; Salmonella; Endocytic cycle; Salmonella enterica; Vacuole; Mannose receptor; Transferrin receptor; Cell biology; Siderophore; Ferritin; DMT1; Biology; Chemistry; Biochemistry; Transferrin; Endocytosis; Macrophage; Receptor; Cytoplasm; Transporter; In vitro; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001471809,0.0001891649,0.0002010274,0.0000908561,0.0001133993,0.0001962098,0.000110512,0.0002331476,0.0007410125],"category_scores_gemma":[0.0001297831,0.0001009684,0.0002003628,0.00005469918,0.0001575273,0.0001289102,0.0001346128,0.0002483856,0.0002725844],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002550208,"about_ca_system_score_gemma":0.00009321195,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005550547,"about_ca_topic_score_gemma":0.0005897928,"domain_scores_codex":[0.9999101,0.00001861039,0.000007847915,0.00001323253,0.0000146806,0.00003551301],"domain_scores_gemma":[0.9999143,0.00002036344,0.00002160504,0.000007699942,0.00001333547,0.00002270582],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001168863,0.000008066145,0.00006152417,0.00001379194,0.000001287329,0.00001483684,0.000006751081,0.000008013232,0.9994602,0.00001482544,0.00001374949,0.0002801833],"study_design_scores_gemma":[0.00001475004,0.0002556864,0.004152764,0.000004045904,0.000007599987,0.0001089563,0.0000231605,0.0002165891,0.9944547,0.00001759062,0.0007418234,0.000002456803],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977678,0.0006837058,0.0004532985,0.00006491879,0.00001172811,0.00001404405,0.0001038352,0.00002613737,0.0008744485],"genre_scores_gemma":[0.9976522,0.0005219801,0.0005799278,0.00007629389,0.000007396784,0.00001556032,0.000153804,0.0000147384,0.0009782106],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007410125,"threshold_uncertainty_score":0.002478898,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03992845995428498,"score_gpt":0.2791761433139753,"score_spread":0.2392476833596903,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}