{"id":"W2065162032","doi":"10.1073/pnas.0937287100","title":"Iron chelators modulate the fusogenic properties of <i>Salmonella</i> -containing phagosomes","year":2003,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Iron Metabolism and Disorders","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; SickKids Foundation; Hospital for Sick Children","funders":"Canadian Institutes of Health Research; U.S. Public Health Service; National Institutes of Health","keywords":"Phagosome; Endosome; Intracellular; Salmonella; Endocytic cycle; Salmonella enterica; Vacuole; Mannose receptor; Transferrin receptor; Cell biology; Siderophore; Ferritin; DMT1; Biology; Chemistry; Biochemistry; Transferrin; Endocytosis; Macrophage; Receptor; Cytoplasm; Transporter; In vitro; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001309707,0.00009700722,0.0002055471,0.0001079826,0.00015851,0.000009109533,0.0003862974,0.00006297928,0.00001407983],"category_scores_gemma":[0.0006598553,0.00004783089,0.0001057491,0.0005815509,0.001075934,0.0002258101,0.00005326805,0.0001428939,0.00000100276],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001296987,"about_ca_system_score_gemma":0.00006781456,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007496818,"about_ca_topic_score_gemma":2.882724e-8,"domain_scores_codex":[0.9983081,0.000009364231,0.0003406286,0.0001725337,0.001012834,0.000156606],"domain_scores_gemma":[0.9993318,0.00004206815,0.0003676937,0.00001265413,0.0002153172,0.00003042901],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006598562,0.00008022438,0.02765988,0.0002552413,0.00002130934,4.612595e-9,0.001081616,0.0001380968,0.9055694,0.06457017,0.0001928834,0.0003652178],"study_design_scores_gemma":[0.0005149266,0.00007858166,0.04229144,0.0001238128,0.00006811613,0.00001238894,0.001830409,0.0001804819,0.9446562,0.00991213,0.0002529969,0.00007851752],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9834753,0.002596554,2.718123e-7,0.001798108,0.00002441849,0.0002299195,0.000002131271,0.000007577247,0.01186568],"genre_scores_gemma":[0.9989157,0.0001241994,0.0002775149,0.0003536965,0.00003469455,0.000007024171,3.972273e-8,0.000005108212,0.000282058],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05465804,"threshold_uncertainty_score":0.3964323,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03992845995428498,"score_gpt":0.2791761433139753,"score_spread":0.2392476833596903,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}