{"id":"W2065203200","doi":"10.1186/1742-4690-9-s2-p348","title":"DNA vaccines that express the MPER of HIV-1 gp41 elicit different antibodies depending upon their transmembrane and cytoplasmic domains","year":2012,"lang":"en","type":"article","venue":"Retrovirology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"","keywords":"Gp41; Transmembrane protein; Cytoplasm; Antibody; Epitope; Virology; Human immunodeficiency virus (HIV); DNA vaccination; Immunology; Medicine; Biology; Cell biology; Genetics; Immunization; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000227631,0.0002475344,0.0004566231,0.0001223491,0.0002366976,0.000009132264,0.0002263011,0.0002407363,0.0003870609],"category_scores_gemma":[0.00003107458,0.0001342212,0.0001131832,0.00005579113,0.0002928976,0.00009483888,0.0001158827,0.0002971998,0.0001236119],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002520833,"about_ca_system_score_gemma":0.00001430903,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004601296,"about_ca_topic_score_gemma":0.00006507378,"domain_scores_codex":[0.9983714,0.0004125077,0.0002259578,0.000249865,0.00004933294,0.000690932],"domain_scores_gemma":[0.9989396,0.0005630292,0.00009292446,0.000332351,0.0000202606,0.00005186537],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003736317,0.0001750955,0.2955571,0.00004037228,0.0003703719,0.000004175535,0.00128324,8.319229e-7,0.699442,0.0005404264,0.0002629875,0.001949721],"study_design_scores_gemma":[0.00283747,0.0005043361,0.5053114,0.00002555214,0.0001256158,0.0002850919,0.0006495662,0.000004645679,0.479848,0.0000951245,0.01010983,0.0002033651],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9883555,0.009750485,0.000143671,0.0006507186,0.0002463066,0.0002888622,0.0001511384,0.0000334868,0.0003798013],"genre_scores_gemma":[0.9973223,0.002002042,0.00001544647,0.00006715875,0.00004907011,0.00003516438,0.0001075066,0.00001936705,0.0003819381],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.219594,"threshold_uncertainty_score":0.5473382,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01646638133652084,"score_gpt":0.2436288502509087,"score_spread":0.2271624689143879,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}