{"id":"W2065229355","doi":"10.4161/hv.24256","title":"Immunogenicity of an investigational hepatitis B vaccine (hepatitis B surface antigen co-administered with an immunostimulatory phosphorothioate oligodeoxyribonucleotide) in nonresponders to licensed hepatitis B vaccine","year":2013,"lang":"en","type":"article","venue":"Human Vaccines & Immunotherapeutics","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; Capital District Health Authority; Institut National de Santé Publique du Québec; Izaak Walton Killam Health Centre; Dalhousie University","funders":"","keywords":"HBsAg; Medicine; Immunogenicity; Hepatitis B; Vaccination; Hepatitis B vaccine; Adjuvant; Hepatitis A vaccine; Immunology; Antibody; Hepatitis B virus; Internal medicine; Virology; Gastroenterology; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002622312,0.0003063742,0.0006477173,0.0001283594,0.0001352928,0.0002169187,0.0001951083,0.0003940505,0.0005904915],"category_scores_gemma":[0.001438237,0.000263001,0.0005963652,0.0001248485,0.0002655534,0.0002590335,0.0001393805,0.0005952935,0.0001756328],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001941643,"about_ca_system_score_gemma":0.0002013022,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000392107,"about_ca_topic_score_gemma":0.0005215443,"domain_scores_codex":[0.999248,0.0004996596,0.0000603036,0.00006101741,0.00006979733,0.00006124034],"domain_scores_gemma":[0.9990441,0.0004054638,0.0002016466,0.0001240941,0.00009874744,0.0001259734],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.2073905,0.03138631,0.2894835,0.0007649463,0.00130025,0.0007017707,0.001447968,0.001599485,0.3860011,0.00009617377,0.0005826515,0.07924539],"study_design_scores_gemma":[0.005922715,0.6144966,0.3412673,0.00002864039,0.0006869215,0.0008424999,0.0002133606,0.001525615,0.03420402,0.00004382421,0.0007521852,0.00001632919],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9997978,0.00007746405,0.00004269404,0.000003279808,0.000002487225,0.00001530167,0.00001013042,0.000001684665,0.00004918738],"genre_scores_gemma":[0.9996347,0.00006088039,0.00008456816,0.00001772873,0.000006938382,0.00002703989,0.00005122469,0.000001184145,0.0001155752],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002622312,"threshold_uncertainty_score":0.01386827,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02828316372286493,"score_gpt":0.3071396754623606,"score_spread":0.2788565117394957,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}