{"id":"W2065243148","doi":"10.1016/j.antiviral.2007.08.001","title":"Porcine plasma ficolin binds and reduces infectivity of porcine reproductive and respiratory syndrome virus (PRRSV) in vitro","year":2007,"lang":"en","type":"article","venue":"Antiviral Research","topic":"Animal Virus Infections Studies","field":"Agricultural and Biological Sciences","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"Canadian Institutes of Health Research","keywords":"Ficolin; Porcine reproductive and respiratory syndrome virus; Recombinant DNA; Collectin; Lectin pathway; Biology; Lectin; Complement system; Arterivirus; In vitro; Innate immune system; Virus; Glycoprotein; Virology; Molecular biology; Immune system; Mannan-binding lectin; Biochemistry; Classical complement pathway; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003365587,0.0004875366,0.0003389299,0.0004791691,0.0003756729,0.0005723376,0.000535513,0.0006593626,0.001679947],"category_scores_gemma":[0.0006051285,0.0003292387,0.0004356266,0.0002159708,0.00031929,0.0002724072,0.0003531803,0.0005525187,0.0006078766],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006208213,"about_ca_system_score_gemma":0.0003540716,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006158459,"about_ca_topic_score_gemma":0.003095686,"domain_scores_codex":[0.9993501,0.000188656,0.00003051175,0.00006985362,0.000138106,0.0002227882],"domain_scores_gemma":[0.9995903,0.0002323396,0.00003539749,0.00003912316,0.00004677899,0.00005597255],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002879671,0.00006726389,0.0002498697,0.00004347826,0.00001016254,0.00006101297,0.0000403781,0.00006843204,0.9984799,0.00004429151,0.00008581671,0.0005615935],"study_design_scores_gemma":[0.00002218713,0.0006490991,0.01203443,0.000009769123,0.00002561011,0.0003609809,0.00007367644,0.0009257092,0.9836009,0.00003572528,0.002249815,0.00001218635],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950275,0.001690874,0.0009748382,0.00009188589,0.00004586054,0.00002161913,0.0001810781,0.00003748594,0.001928823],"genre_scores_gemma":[0.9919681,0.0007277051,0.001110244,0.0002030138,0.00004530667,0.00002160272,0.001613718,0.00003014991,0.00428028],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006158459,"threshold_uncertainty_score":0.01224524,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08025344957853148,"score_gpt":0.3493860978206842,"score_spread":0.2691326482421527,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}