{"id":"W2065268020","doi":"10.1056/nejmct1004810","title":"Iron-Chelating Therapy for Transfusional Iron Overload","year":2011,"lang":"en","type":"review","venue":"New England Journal of Medicine","topic":"Hemoglobinopathies and Related Disorders","field":"Medicine","cited_by":361,"is_retracted":false,"has_abstract":true,"ca_institutions":"Columbia College","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; U.S. Food and Drug Administration","keywords":"Chelation; Chelation therapy; Intracellular; Urine; Anemia; Sickle cell anemia; Medicine; Excretion; Red Cell; Cell; Chemistry; Gastroenterology; Internal medicine; Biochemistry; Inorganic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003380856,0.0007136912,0.001291429,0.00234496,0.0002878598,0.0003783579,0.0008582274,0.0007622554,0.001876955],"category_scores_gemma":[0.0006556545,0.0002138767,0.0004167646,0.001809626,0.0003326373,0.0005744904,0.0003960784,0.001188307,0.001399484],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002927461,"about_ca_system_score_gemma":0.0004127173,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009049993,"about_ca_topic_score_gemma":0.002013688,"domain_scores_codex":[0.9998598,0.00003039276,0.00002764108,0.00002118638,0.00004897974,0.00001194649],"domain_scores_gemma":[0.9997304,0.0001429357,0.00004656512,0.000007858636,0.00005117486,0.00002105818],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008956917,0.0001077492,0.0002814472,0.01096086,0.0001370087,0.0009694667,0.00005180989,0.000159396,0.001412631,0.0005077566,0.02380022,0.961522],"study_design_scores_gemma":[0.0001366599,0.0003598058,0.005284235,0.01029868,0.0006282543,0.02908142,0.0001726923,0.0002813411,0.002388514,0.00153864,0.9497805,0.00004915451],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002558437,0.9989048,0.00009173319,0.00010032,0.00008249506,0.000003237998,0.000007702093,0.000006119826,0.0005477149],"genre_scores_gemma":[0.001833995,0.9973537,0.0001759424,0.0001353303,0.0001034261,0.000004755253,0.00002773029,0.000001715073,0.0003633802],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00234496,"threshold_uncertainty_score":0.006279051,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04999037846515916,"score_gpt":0.3290637312367001,"score_spread":0.2790733527715409,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}