{"id":"W2065271738","doi":"10.1097/aln.0b013e3181ee2ceb","title":"Pros and Cons of Composite Endpoints in Anesthesia Trials","year":2010,"lang":"en","type":"editorial","venue":"Anesthesiology","topic":"Cardiac, Anesthesia and Surgical Outcomes","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Medicine; cons; Anesthesia; Clinical trial; Intensive care medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.002878681,0.000515489,0.005420146,0.0004421017,0.00004050815,0.0000159284,0.0002015921,0.002593214,0.0001091706],"category_scores_gemma":[0.004161821,0.0003881353,0.0006689132,0.0001840929,0.0006202118,0.00004135532,0.00004605484,0.001391926,0.00002950409],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000364999,"about_ca_system_score_gemma":0.0004753062,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000212525,"about_ca_topic_score_gemma":0.00003253429,"domain_scores_codex":[0.9959075,0.001030331,0.001422269,0.0006723795,0.0004840535,0.0004834609],"domain_scores_gemma":[0.9863299,0.01199658,0.0006153435,0.0006180619,0.0002124931,0.0002276474],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01005274,0.001248078,0.4314031,0.002731225,0.000933186,0.02021938,0.001279464,0.000001400677,0.01481839,0.002744274,0.5045639,0.0100049],"study_design_scores_gemma":[0.003190167,0.0007441337,0.08598357,0.0002833822,0.0004631548,0.001486143,0.00003233974,0.000001578031,0.0007062881,0.0001143211,0.906639,0.0003558557],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"editorial","genre_scores_codex":[0.8975683,0.002507812,0.000001020494,0.001225604,0.09512026,0.001859109,0.00002916386,0.00008249054,0.001606204],"genre_scores_gemma":[0.2322206,0.007552621,0.0025541,0.002384736,0.7450069,0.0005540368,0.001935286,0.0004798567,0.007311866],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.6653477,"threshold_uncertainty_score":0.9998571,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01926203904172314,"score_gpt":0.3223887722523205,"score_spread":0.3031267332105974,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}