{"id":"W2065301559","doi":"10.1038/cr.2012.58","title":"K48-linked ubiquitination and protein degradation regulate 53BP1 recruitment at DNA damage sites","year":2012,"lang":"en","type":"article","venue":"Cell Research","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Biology; DNA damage; Ubiquitin; DNA repair; DNA; Cell biology; Genetics; Molecular biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001408928,0.0001065379,0.00008062067,0.00008392295,0.0001840179,0.00003869814,0.0001298699,0.0001507318,0.00007909105],"category_scores_gemma":[0.0001428171,0.0001021178,0.00003136736,0.0001146701,0.00008480014,0.00001204525,0.0003440288,0.0001214692,0.00006738309],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007822964,"about_ca_system_score_gemma":0.00003844445,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008509647,"about_ca_topic_score_gemma":0.00001393251,"domain_scores_codex":[0.9985034,0.0002765463,0.0001389897,0.0003036565,0.0003388463,0.0004385171],"domain_scores_gemma":[0.9992598,0.00002656085,0.00004536255,0.0003542768,0.000158546,0.0001554795],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004251955,0.00006887074,0.0003735462,0.0000417784,0.000008709628,0.000001324771,0.00007199949,5.89678e-7,0.9948058,0.0003412871,0.001161769,0.003081767],"study_design_scores_gemma":[0.0003150898,0.0002359037,0.001760026,0.00001115612,0.000004433543,0.000003122154,0.00007069599,0.0001102793,0.9608967,0.0001865405,0.03629503,0.0001109977],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930007,0.0006108417,0.0001196937,0.0001717745,0.0000401957,0.0009691765,0.000006145241,0.00001734271,0.005064064],"genre_scores_gemma":[0.9635404,0.00009590913,0.001059978,0.0000240874,0.000162321,0.0002083175,0.0002686319,0.00002513038,0.03461519],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03513326,"threshold_uncertainty_score":0.4164242,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1108444691788452,"score_gpt":0.3607393949519573,"score_spread":0.2498949257731122,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}