{"id":"W2065426711","doi":"10.1016/j.bpj.2012.10.028","title":"Autofluorescence Imaging of Living Pancreatic Islets Reveals Fibroblast Growth Factor-21 (FGF21)-Induced Metabolism","year":2012,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Fibroblast Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research","keywords":"FGF21; Pancreatic islets; Endocrinology; Internal medicine; Acetyl-CoA carboxylase; Biology; Fatty acid; Fatty acid metabolism; Pyruvate carboxylase; Carbohydrate metabolism; Insulin; Metabolism; Chemistry; Biochemistry; Islet; Fibroblast growth factor; Enzyme; Receptor; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001299661,0.0001919848,0.000223846,0.0001590189,0.0002849191,0.0004012538,0.0002119494,0.0003446758,0.001018426],"category_scores_gemma":[0.0001085493,0.0001538585,0.0002133861,0.0001794664,0.0002312891,0.0002723869,0.0001996486,0.0007101454,0.0002263232],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004136896,"about_ca_system_score_gemma":0.0002185702,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001206962,"about_ca_topic_score_gemma":0.001365563,"domain_scores_codex":[0.9999268,0.000007371917,0.000003119294,0.00001806077,0.00002121609,0.00002346903],"domain_scores_gemma":[0.9999161,0.00002619847,0.00001098735,0.00001198544,0.00001282546,0.00002193911],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001068063,0.00001420523,0.0001738584,0.00001366812,0.000003306948,0.00009176235,0.00002004088,0.00006634706,0.9980289,0.0001482267,0.0000552206,0.001277577],"study_design_scores_gemma":[0.0000146189,0.0000357034,0.006576961,0.000003655045,0.000006682541,0.0002260113,0.00004066743,0.001328547,0.9904193,0.0001116242,0.001231033,0.000005082044],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9861124,0.001130536,0.008849275,0.0002135095,0.00005067345,0.0000146689,0.0002431238,0.0000898861,0.003295866],"genre_scores_gemma":[0.985153,0.001570213,0.00869444,0.0001397824,0.00002953948,0.00004261314,0.0003119222,0.00007989202,0.003978646],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001206962,"threshold_uncertainty_score":0.003407001,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01556893272169456,"score_gpt":0.2731353261133306,"score_spread":0.2575663933916361,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}