{"id":"W2065429310","doi":"10.1038/ni.1651","title":"Mincle is an ITAM-coupled activating receptor that senses damaged cells","year":2008,"lang":"en","type":"article","venue":"Nature Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":738,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Cell biology; Chemokine; Infiltration (HVAC); Receptor; Biology; Inflammation; Innate immune system; Proinflammatory cytokine; Programmed cell death; Immunology; Chemistry; Apoptosis; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001947548,0.0005811839,0.0004563692,0.0003418711,0.000388327,0.0007027474,0.0004908017,0.0008429294,0.002512721],"category_scores_gemma":[0.0002010369,0.0002289059,0.0003716013,0.0001493224,0.0003373554,0.0006500813,0.0007009663,0.001111281,0.001178023],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004056484,"about_ca_system_score_gemma":0.0001591749,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001502347,"about_ca_topic_score_gemma":0.0002320921,"domain_scores_codex":[0.9997799,0.0000245811,0.000008016324,0.00005238858,0.00005200196,0.00008324127],"domain_scores_gemma":[0.9998555,0.00001799902,0.0000420247,0.00001223506,0.00001895866,0.00005317378],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000333971,0.00003819475,0.0005624628,0.00009953683,0.00001376502,0.0002101942,0.00002333423,0.0000540001,0.9907913,0.0008150262,0.0007104871,0.006347597],"study_design_scores_gemma":[0.00008700033,0.0006264747,0.01000936,0.00003133538,0.0000473189,0.002653643,0.00009438916,0.001783308,0.9542661,0.0008264909,0.02954182,0.00003267775],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9360024,0.01997967,0.0246135,0.001557518,0.0008368617,0.000151951,0.0008108443,0.0008956353,0.01515172],"genre_scores_gemma":[0.9609857,0.006435234,0.01184605,0.0008559148,0.0003916681,0.00009270616,0.001919912,0.0001029637,0.01736992],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002512721,"threshold_uncertainty_score":0.008405924,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01703622834688125,"score_gpt":0.2501177777280186,"score_spread":0.2330815493811373,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}