{"id":"W2065475918","doi":"10.1016/j.bmc.2011.05.033","title":"Mapping the intestinal alpha-glucogenic enzyme specificities of starch digesting maltase-glucoamylase and sucrase-isomaltase","year":2011,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry","topic":"Enzyme Production and Characterization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":85,"is_retracted":false,"has_abstract":false,"ca_institutions":"Simon Fraser University; University of Waterloo","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research","keywords":"Maltase; Sucrase; Chemistry; Acarbose; Alpha-glucosidase; Biochemistry; Glucosidases; Protein subunit; Enzyme; Maltose; Starch; Endocrinology; Gene; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003296353,0.0002117161,0.0001838272,0.00003245897,0.0001281131,0.00001362793,0.0002378854,0.0001185102,0.000339708],"category_scores_gemma":[0.0003361743,0.0001699651,0.00005365819,0.0001646556,0.0003768477,0.000008520024,0.000147655,0.0001931396,0.000004521938],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001713237,"about_ca_system_score_gemma":0.0001208542,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003883994,"about_ca_topic_score_gemma":0.000003557283,"domain_scores_codex":[0.9987149,0.00004689375,0.0003768248,0.0003915912,0.0002063795,0.0002633648],"domain_scores_gemma":[0.9991189,0.00002857762,0.0002131922,0.0003778411,0.0001358017,0.0001256397],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001280987,0.00005974975,0.004345619,0.0001530034,0.00003721604,0.00001003169,0.000477557,1.71261e-7,0.9932927,0.00001581887,0.0003005772,0.001179487],"study_design_scores_gemma":[0.0003943437,0.0001460636,0.007931835,0.00007789955,0.00003309827,0.0003090525,0.002158514,0.00001528289,0.9859403,0.00002181933,0.002789581,0.0001821685],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962284,0.002048302,0.0004885137,0.0002385017,0.0001125466,0.0001259867,0.00003121272,0.0000246168,0.0007019289],"genre_scores_gemma":[0.9980168,0.0003060166,0.0003230553,0.0001410103,0.0006052887,0.00001050064,0.0001738847,0.00002764207,0.0003958479],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007352327,"threshold_uncertainty_score":0.6930977,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03812665791107089,"score_gpt":0.2229160825413034,"score_spread":0.1847894246302325,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}