{"id":"W2065519679","doi":"10.1006/jmcc.1999.1068","title":"Changes in Gene Expression with Iron Loading and Chelation in Cardiac Myocytes and Non-myocytic Fibroblasts","year":2000,"lang":"en","type":"article","venue":"Journal of Molecular and Cellular Cardiology","topic":"Iron Metabolism and Disorders","field":"Medicine","cited_by":50,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Deferoxamine; Biglycan; Myocyte; Gene expression; Fibrosis; Transferrin receptor; Endocrinology; Internal medicine; Chemistry; Decorin; Cardiac fibrosis; Transferrin; Molecular biology; Biology; Gene; Biochemistry; Extracellular matrix; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002821292,0.0001144948,0.0004653994,0.0001823835,0.00002160027,0.000008920613,0.00002225854,0.0001100021,0.000006963329],"category_scores_gemma":[0.00001686246,0.00008709665,0.00004016251,0.00007770486,0.00007316296,0.0000555073,0.00001536419,0.0001791757,3.741976e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001588887,"about_ca_system_score_gemma":0.00002734847,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001548786,"about_ca_topic_score_gemma":0.000004416661,"domain_scores_codex":[0.9992773,0.0001140301,0.0001909516,0.0001506696,0.0001081474,0.0001589137],"domain_scores_gemma":[0.9997218,0.00002488768,0.00006599493,0.0000773987,0.0000231192,0.0000867972],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0006453078,0.00001916392,0.1230864,0.0001256635,0.00002829622,0.0007890498,0.0006625126,0.0004188978,0.867668,0.000005951712,0.00001139429,0.006539293],"study_design_scores_gemma":[0.01241419,0.001904117,0.5037097,0.00069972,0.0004861032,0.002133182,0.001848319,0.0002621788,0.4753056,0.0001893982,0.0005924221,0.0004550153],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9803338,0.01875236,0.0003346496,0.0001389969,0.00003161515,0.0001228913,8.689867e-7,0.000002063875,0.0002827315],"genre_scores_gemma":[0.9957417,0.003537918,0.0005328709,0.00007570212,0.00007180782,0.000002304015,0.000003899716,0.0000112329,0.00002252964],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3923624,"threshold_uncertainty_score":0.3551698,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004308298155662337,"score_gpt":0.2030871439420384,"score_spread":0.1987788457863761,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}