{"id":"W2065531004","doi":"10.1002/ijc.22371","title":"TAP expression reduces IL‐10 expressing tumor infiltrating lymphocytes and restores immunosurveillance against melanoma","year":2007,"lang":"en","type":"article","venue":"International Journal of Cancer","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"","keywords":"Immunosurveillance; Antigen; Immunogenicity; Immunology; Cancer research; Antigen presentation; Biology; Immunotherapy; Melanoma; Immune system; MHC class I; Major histocompatibility complex; T cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009948602,0.0003867788,0.0002662531,0.0002093506,0.00008360041,0.0002578945,0.0002167856,0.0003013331,0.001226225],"category_scores_gemma":[0.0001285637,0.0001162306,0.0001560545,0.00008434053,0.0001759985,0.0001612926,0.000136212,0.0008768823,0.0004492032],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001833612,"about_ca_system_score_gemma":0.0001910897,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004816143,"about_ca_topic_score_gemma":0.0005809286,"domain_scores_codex":[0.9998355,0.00002608778,0.0000146687,0.00002129268,0.00004389777,0.00005854026],"domain_scores_gemma":[0.9998432,0.00002755435,0.00002981633,0.00001719181,0.00001411003,0.00006815399],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009584022,0.00007781811,0.00008207629,0.00001625781,0.000002339108,0.00003204213,0.000007339376,0.00003943708,0.9986976,0.00002017367,0.00003724823,0.0008916952],"study_design_scores_gemma":[0.00004290927,0.001467129,0.002690018,0.000007072204,0.00002017213,0.0004259579,0.00003464098,0.0009195985,0.9927806,0.00004022343,0.001567663,0.000004038507],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972956,0.0006427213,0.0009468967,0.00009957805,0.00003885819,0.00001814984,0.0001041484,0.00009936347,0.0007547393],"genre_scores_gemma":[0.9966342,0.0004711388,0.000717391,0.000052322,0.00001785711,0.0000188398,0.0002735121,0.00002905392,0.001785752],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001226225,"threshold_uncertainty_score":0.004102111,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01079261770147858,"score_gpt":0.293246244200037,"score_spread":0.2824536264985584,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}