{"id":"W2065612246","doi":"10.1016/j.bbrc.2010.09.083","title":"Diaryl dimers of estradiol and of estrone may be formed as major metabolites by mouse mammary glands","year":2010,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Metabolite; Chemistry; Estrone; Saponification; Estrogen; Ether; Stearate; Biochemistry; High-performance liquid chromatography; Microsome; Chromatography; Endocrinology; Hormone; Organic chemistry; Enzyme; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002407783,0.000498582,0.0002663151,0.0005517566,0.0001853342,0.0003879254,0.0003304049,0.000450835,0.001790383],"category_scores_gemma":[0.0002444101,0.0004928192,0.0003128687,0.0002510575,0.0002404874,0.0004692949,0.00024997,0.0006151625,0.0006805426],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000304435,"about_ca_system_score_gemma":0.0001993167,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001949374,"about_ca_topic_score_gemma":0.0003749345,"domain_scores_codex":[0.9998277,0.00002766135,0.00001176414,0.00005337379,0.000035505,0.0000438624],"domain_scores_gemma":[0.9996146,0.00006319917,0.0001175984,0.00006426044,0.00003318021,0.0001071569],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001757673,0.00001050135,0.0001641502,0.00001241522,0.000003364405,0.00004166105,0.00001544424,0.00002928123,0.9984462,0.0002343333,0.00001980492,0.0008471879],"study_design_scores_gemma":[0.000006917198,0.00009060489,0.001209087,0.000001877579,0.000007321585,0.00010058,0.00001206115,0.00009423483,0.997408,0.00008003551,0.0009863867,0.000002967076],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9885027,0.002455631,0.006023017,0.0001386677,0.00003782059,0.0000254676,0.0006602966,0.0001198971,0.002036522],"genre_scores_gemma":[0.9865916,0.0009326898,0.002825953,0.00007778002,0.00002368763,0.00004182386,0.001165031,0.00005965928,0.008281694],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001790383,"threshold_uncertainty_score":0.005989373,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01768127354545554,"score_gpt":0.3254228364883459,"score_spread":0.3077415629428903,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}