{"id":"W2065728490","doi":"10.1016/j.bbr.2007.01.005","title":"The neurosteroid THDOC differentially affects spatial behavior and anesthesia in Slow and Fast kindling rat strains","year":2007,"lang":"en","type":"article","venue":"Behavioural Brain Research","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University; Carleton University","funders":"Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"Neuroactive steroid; GABAA receptor; Allopregnanolone; Pregnanolone; Inhibitory postsynaptic potential; Neuroscience; Kindling; Endocrinology; Epileptogenesis; Benzodiazepine; Morris water navigation task; Receptor; Internal medicine; Psychology; Chemistry; Hippocampus; Biology; Medicine; Epilepsy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.003202008,0.000279261,0.00024985,0.000524284,0.001391799,0.000620297,0.0007961107,0.0001368392,0.00001500005],"category_scores_gemma":[0.001164234,0.0002080589,0.00005434162,0.000885073,0.002003691,0.0003248693,0.0005840866,0.001654826,0.00001292737],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005589244,"about_ca_system_score_gemma":0.0001170602,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001096341,"about_ca_topic_score_gemma":0.0006428586,"domain_scores_codex":[0.9939994,0.001575709,0.0003517435,0.001049548,0.001325991,0.001697645],"domain_scores_gemma":[0.9956762,0.003345649,0.00006717605,0.0003951665,0.00007639507,0.0004394312],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001867157,0.0001530732,0.07453618,0.00001051969,5.548578e-7,0.004258402,0.0002267188,3.678718e-7,0.8942838,0.0001351234,0.00009884524,0.02610969],"study_design_scores_gemma":[0.0009951207,0.0006548217,0.6525513,0.00001757083,0.000005746346,0.0008215249,0.0001248163,0.0001618991,0.3442667,0.00003241202,0.0001726681,0.0001954093],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948131,0.00006199467,0.000008304669,0.00343064,0.0002194927,0.001330436,0.00000548463,0.00005053641,0.00007995419],"genre_scores_gemma":[0.9981515,0.0001959387,0.000005102118,0.0005214053,0.00007887936,0.00009559884,8.87719e-7,0.00004366899,0.000907046],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5780151,"threshold_uncertainty_score":0.9999083,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1145456884060996,"score_gpt":0.3999838550530299,"score_spread":0.2854381666469302,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}