{"id":"W2065755593","doi":"10.1042/0264-6021:3540199","title":"Roles of aggrecan domains in biosynthesis, modification by glycosaminoglycans and product secretion","year":2001,"lang":"en","type":"article","venue":"Biochemical Journal","topic":"Proteoglycans and glycosaminoglycans research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre; University of Toronto","funders":"Medical Research Council; Medical Research Council Canada; Arthritis Society; Canadian Arthritis Network; University of Calgary","keywords":"Aggrecan; Secretion; Proteoglycan; Glycosaminoglycan; Immunoglobulin D; Chemistry; Biochemistry; Peptide sequence; N-terminus; Cell biology; Biology; Molecular biology; Gene; Genetics; Extracellular matrix","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004132579,0.0001678435,0.0001949537,0.00012891,0.00006753167,0.00003532831,0.0002381402,0.0001652192,0.00002090899],"category_scores_gemma":[0.000210383,0.0001510338,0.00006827551,0.0002013543,0.0002033171,0.00001065616,0.00007720945,0.000224709,0.00000133456],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004186423,"about_ca_system_score_gemma":0.0001032358,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005106755,"about_ca_topic_score_gemma":0.0000380678,"domain_scores_codex":[0.9985742,0.0001003997,0.0003726992,0.0003511789,0.0002639945,0.0003375076],"domain_scores_gemma":[0.9992893,0.00001652688,0.000148628,0.0002485443,0.0001184167,0.0001785229],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003465389,0.0001331698,0.007482843,0.00001812072,0.00002360848,0.000007150407,0.0000352157,0.000003365898,0.9716879,0.00002366388,0.00133999,0.01889841],"study_design_scores_gemma":[0.0008661008,0.0002267273,0.004176467,0.00006021428,0.00001115915,0.0003056361,0.00009354478,0.0001298028,0.9808271,0.0001429703,0.01295893,0.0002013707],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924073,0.005414509,0.001077583,0.0005974515,0.00003817713,0.0001932709,0.00003517346,0.000005143306,0.0002314521],"genre_scores_gemma":[0.9940358,0.004843542,0.0006124135,0.00004153819,0.000204401,0.00001567785,0.00008603062,0.00001855627,0.0001420105],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01869704,"threshold_uncertainty_score":0.6158979,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01257334529014638,"score_gpt":0.2704160021269186,"score_spread":0.2578426568367722,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}