{"id":"W2065822074","doi":"10.1371/journal.pone.0091872","title":"Short-Chain Flavor Ester Synthesis in Organic Media by an E. coli Whole-Cell Biocatalyst Expressing a Newly Characterized Heterologous Lipase","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Microbial Metabolic Engineering and Bioproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"PROTEO; Innu-Science (Canada); Institut National de la Recherche Scientifique","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biocatalysis; Lipase; Transesterification; Chemistry; Organic chemistry; Methanol; Biochemistry; Enzyme; Catalysis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002848986,0.0002046991,0.0002896592,0.00006310863,0.000043975,0.00004157285,0.0001811144,0.0002034203,0.00002111187],"category_scores_gemma":[0.0001914207,0.0002017511,0.00004420433,0.00008725381,0.00004523182,0.00001099388,0.00006179607,0.0001246582,0.00001896934],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001442911,"about_ca_system_score_gemma":0.00001558974,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000168708,"about_ca_topic_score_gemma":0.00003180586,"domain_scores_codex":[0.9987213,0.0001133826,0.000254179,0.0004753605,0.0001171109,0.0003186501],"domain_scores_gemma":[0.9993083,0.00001098515,0.00006135803,0.0004597084,0.00003694777,0.0001226603],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007820411,0.0006147995,0.0001603578,0.00005517389,0.00003460511,0.000001368969,0.00006892577,0.000004996318,0.9973792,2.553179e-7,0.0001156961,0.00148646],"study_design_scores_gemma":[0.0003856504,0.000103666,0.0005028631,0.00006162741,0.0000572872,0.000003769211,0.00001512478,0.0002362915,0.9967172,9.652694e-7,0.001673253,0.0002423688],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984648,0.0002836372,0.0006729579,0.0001955509,0.0001028813,0.0001767021,0.00004293659,0.0000402038,0.00002034213],"genre_scores_gemma":[0.997551,0.0001117163,0.0008643339,0.0001479193,0.0005669023,0.00004501801,0.0003996173,0.00004618705,0.000267282],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001557557,"threshold_uncertainty_score":0.8227172,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01373804728591408,"score_gpt":0.1910833050671467,"score_spread":0.1773452577812326,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}