{"id":"W2065849940","doi":"10.1242/jcs.01421","title":"Insulin but not PDGF relies on actin remodeling and on VAMP2 for GLUT4 translocation in myoblasts","year":2004,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; University of Toronto; Hospital for Sick Children","funders":"","keywords":"GLUT4; Biology; Cell biology; Cytochalasin D; Actin remodeling; Actin cytoskeleton; Exocytosis; Platelet-derived growth factor receptor; Myocyte; Insulin; Actin; Glucose transporter; Cytoskeleton; Endocrinology; Cell; Growth factor; Biochemistry; Secretion; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001472556,0.0002836777,0.0002601153,0.0001686677,0.0002121095,0.0003316243,0.0001890185,0.0002572033,0.001018862],"category_scores_gemma":[0.0001233428,0.0002290935,0.000262822,0.0001927307,0.0002031122,0.0001746276,0.000227738,0.0006628212,0.0007192402],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003309645,"about_ca_system_score_gemma":0.0003340107,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001503871,"about_ca_topic_score_gemma":0.00284578,"domain_scores_codex":[0.9998003,0.00002647385,0.00002771535,0.00004599139,0.00005419177,0.00004526127],"domain_scores_gemma":[0.999871,0.00002530132,0.00002338242,0.00001972644,0.00001618866,0.00004439981],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001875351,0.00001727759,0.0001197165,0.00002565958,0.000002703086,0.00003273505,0.000009114561,0.00001758493,0.9988822,0.0000353854,0.0000375195,0.0006325181],"study_design_scores_gemma":[0.00006148416,0.000256349,0.01505554,0.00001110184,0.00002121151,0.0001732487,0.00004615591,0.0006129097,0.9798876,0.00003510355,0.003833137,0.000006200832],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896786,0.002751853,0.001373713,0.0002207278,0.00008582729,0.00003803974,0.0007741226,0.00008472122,0.004992545],"genre_scores_gemma":[0.9868441,0.002294913,0.002723868,0.0001789771,0.00003177474,0.0001068032,0.0008683692,0.00004638912,0.006904833],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001503871,"threshold_uncertainty_score":0.003408372,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01351686491251431,"score_gpt":0.261962621260461,"score_spread":0.2484457563479467,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}