{"id":"W2065886242","doi":"10.1038/ncomms7138","title":"Chromatin decompaction by the nucleosomal binding protein HMGN5 impairs nuclear sturdiness","year":2015,"lang":"en","type":"article","venue":"Nature Communications","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":155,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"U.S. National Library of Medicine; National Heart, Lung, and Blood Institute; University of Toronto; National Cancer Institute; National Institutes of Health; Imperial College London; Ariel University; University of Pennsylvania","keywords":"Heterochromatin; Chromatin; Nucleus; Nuclear lamina; Cell nucleus; Biology; Cell biology; Nuclear protein; Histone; Nucleosome; DNA; Genetics; Gene; Transcription factor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001355553,0.0003007451,0.0002199756,0.0002750905,0.00014331,0.000208617,0.0002899216,0.0003285078,0.00148404],"category_scores_gemma":[0.0001438128,0.0001920974,0.0002606838,0.00009731491,0.0003627794,0.0001497202,0.0003190956,0.0003195516,0.0002095935],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002529161,"about_ca_system_score_gemma":0.0002006639,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009983382,"about_ca_topic_score_gemma":0.001627309,"domain_scores_codex":[0.9998602,0.0000236443,0.00002338913,0.00003426065,0.00003348,0.00002504358],"domain_scores_gemma":[0.9997758,0.00003497544,0.00007467884,0.00002721468,0.00001074437,0.00007653915],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006548563,0.00001824258,0.0001966821,0.00001710867,0.000004540539,0.00004286084,0.00001256595,0.00005471351,0.998912,0.00009671431,0.00001495542,0.0005641893],"study_design_scores_gemma":[0.00001409319,0.0002374434,0.007619054,0.000006676,0.00001421703,0.0001513492,0.00003320262,0.0007706909,0.9900541,0.00005610137,0.001038709,0.000004440271],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966433,0.0004944669,0.001676636,0.00006718692,0.00002232323,0.00001004425,0.0001810947,0.00008161522,0.0008233641],"genre_scores_gemma":[0.9972141,0.0002734768,0.0007550434,0.00004269392,0.000003246357,0.00001217035,0.0002723993,0.0000219796,0.001404928],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00148404,"threshold_uncertainty_score":0.00496459,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01286659376016462,"score_gpt":0.2729865200096927,"score_spread":0.2601199262495281,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}