{"id":"W2065890382","doi":"10.1038/ng.2270","title":"Detectable clonal mosaicism and its relationship to aging and cancer","year":2012,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Genomic variations and chromosomal abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":594,"is_retracted":false,"has_abstract":false,"ca_institutions":"Mount Sinai Hospital; Public Health Ontario; University of Toronto; Lunenfeld-Tanenbaum Research Institute","funders":"National Cancer Institute; National Institutes of Health; Cancer Research UK","keywords":"Biology; Genetics; Cancer; Evolutionary biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002839072,0.0001191812,0.0001336752,0.001059632,0.0001648083,0.0002147325,0.0002176282,0.0003298589,0.001401327],"category_scores_gemma":[0.0009644373,0.0001540155,0.0001032832,0.0004042469,0.0003513949,0.0002502478,0.0002412498,0.0003069408,0.0000859813],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001487712,"about_ca_system_score_gemma":0.0001328324,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000506769,"about_ca_topic_score_gemma":0.0004496672,"domain_scores_codex":[0.9998839,0.00002950789,0.00001169487,0.0000265575,0.00003099309,0.00001732633],"domain_scores_gemma":[0.9993881,0.0002582183,0.0001739154,0.00006283818,0.00004021812,0.0000766353],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001610924,0.0001056733,0.1491463,0.00009948927,0.00008639574,0.007283512,0.0002957752,0.0005520696,0.804864,0.006807445,0.0005292505,0.02861913],"study_design_scores_gemma":[0.00005764865,0.0009152064,0.8076181,0.00001372984,0.0001231994,0.04628278,0.0002831893,0.002714267,0.1290053,0.007516291,0.005422313,0.0000479823],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926282,0.003017993,0.001983971,0.0001816479,0.0000189177,0.000009441064,0.0001941097,0.00005256676,0.001913209],"genre_scores_gemma":[0.9987864,0.0004124744,0.0003300072,0.00001794315,0.00001620988,0.000003588975,0.00004436214,0.000004567021,0.0003846051],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001401327,"threshold_uncertainty_score":0.004687905,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01021192528241923,"score_gpt":0.2573404000556898,"score_spread":0.2471284747732705,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}