{"id":"W2065890382","doi":"10.1038/ng.2270","title":"Detectable clonal mosaicism and its relationship to aging and cancer","year":2012,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Genomic variations and chromosomal abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":594,"is_retracted":false,"has_abstract":false,"ca_institutions":"Mount Sinai Hospital; Public Health Ontario; University of Toronto; Lunenfeld-Tanenbaum Research Institute","funders":"National Cancer Institute; National Institutes of Health; Cancer Research UK","keywords":"Biology; Genetics; Cancer; Evolutionary biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008683555,0.00008955108,0.00006300319,0.00002638052,0.0001059839,0.00002074714,0.00005055825,0.0001906789,0.00001220058],"category_scores_gemma":[0.00003425942,0.00008769768,0.0000144466,0.00005050574,0.00001354097,0.000004057357,0.00009399642,0.0001224492,0.000002800552],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008865333,"about_ca_system_score_gemma":0.00002512554,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006010339,"about_ca_topic_score_gemma":0.00001905718,"domain_scores_codex":[0.9994884,0.00001769452,0.00008724909,0.0001472298,0.00006377269,0.0001957012],"domain_scores_gemma":[0.9997085,0.000009549244,0.00002519051,0.00009854004,0.00004711168,0.0001111191],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00003176693,0.00003529699,0.7899072,0.00006251054,0.00006863276,7.724743e-7,0.0009118209,0.0002822951,0.1995417,0.002080807,0.001816531,0.005260671],"study_design_scores_gemma":[0.0004327407,0.0001094585,0.5753322,0.00001906002,0.00005997252,0.00005867856,0.0001828913,0.0001307646,0.2646825,0.0002679558,0.1583279,0.0003959104],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9611469,0.03787841,0.0001132966,0.0002627902,0.000179137,0.00008983131,0.00003492252,0.000005490943,0.0002892161],"genre_scores_gemma":[0.9957402,0.0006074831,0.001848022,0.0005023997,0.000437638,0.00001574492,0.00001990138,0.00001250384,0.0008160702],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.214575,"threshold_uncertainty_score":0.3576207,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01021192528241923,"score_gpt":0.2573404000556898,"score_spread":0.2471284747732705,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}