{"id":"W2065909603","doi":"10.1038/labinvest.2010.52","title":"Molecular blockade of VEGFR2 in human epithelial ovarian carcinoma cells","year":2010,"lang":"en","type":"article","venue":"Laboratory Investigation","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"Canadian Institutes of Health Research","keywords":"Small hairpin RNA; Cancer research; Gene knockdown; Downregulation and upregulation; Transfection; Biology; Kinase insert domain receptor; Vascular endothelial growth factor; Vascular endothelial growth factor A; Apoptosis; Cell culture; VEGF receptors","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037034,0.0003635573,0.0003351715,0.0002594826,0.0003211799,0.0004387995,0.0003115486,0.000289216,0.002055998],"category_scores_gemma":[0.0001763608,0.0002192998,0.0003326788,0.0002986925,0.0002139251,0.0002062669,0.0001576321,0.0007193403,0.0004032257],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003994249,"about_ca_system_score_gemma":0.0005456872,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003024811,"about_ca_topic_score_gemma":0.003240271,"domain_scores_codex":[0.9997415,0.00006638547,0.0000212532,0.00003098076,0.00005327999,0.00008664309],"domain_scores_gemma":[0.9999369,0.00002084026,0.000007004728,0.00001385504,0.000008310882,0.00001297295],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005595113,0.0002499516,0.0001531659,0.00009047449,0.000019882,0.0001036617,0.00004641425,0.0003020151,0.9941781,0.000794052,0.000492137,0.003010581],"study_design_scores_gemma":[0.0001601581,0.0007854751,0.001143594,0.000003716574,0.00003014328,0.0002218766,0.00003566086,0.001424504,0.9903237,0.00006674956,0.005800553,0.000003884782],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.983433,0.003537263,0.004035758,0.0006519821,0.0002616679,0.000145474,0.0009776991,0.0001991441,0.006757942],"genre_scores_gemma":[0.990693,0.001425366,0.002036982,0.00009832673,0.00003455044,0.0001261413,0.000770463,0.00001683462,0.004798318],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003024811,"threshold_uncertainty_score":0.006878018,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006888027962804518,"score_gpt":0.2312106322236508,"score_spread":0.2243226042608463,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}