{"id":"W2065931971","doi":"10.1016/j.carres.2008.08.025","title":"Application and limitations of the methyl imidate protection strategy of N-acetylglucosamine for glycosylations at O-4: synthesis of Lewis A and Lewis X trisaccharide analogues","year":2008,"lang":"en","type":"article","venue":"Carbohydrate Research","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":27,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Trisaccharide; N-Acetylglucosamine; Acceptor; Glycosylation; Residue (chemistry); Stereochemistry; Acetylglucosamine; Glucosamine; Monosaccharide; Disaccharide; Organic chemistry; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009446416,0.0004197553,0.0003037025,0.0002323826,0.0002667883,0.0006486434,0.0006289525,0.0004778292,0.0007196629],"category_scores_gemma":[0.0004884534,0.0002169694,0.0003055752,0.00029886,0.0003510052,0.0008719757,0.0003888297,0.0006350033,0.0003525158],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004695889,"about_ca_system_score_gemma":0.0007967759,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001168031,"about_ca_topic_score_gemma":0.001555469,"domain_scores_codex":[0.9997965,0.00005713953,0.00002195484,0.00002776053,0.0000438571,0.00005290761],"domain_scores_gemma":[0.9998356,0.00003954873,0.00004062576,0.00003767225,0.00002273018,0.00002377509],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004577025,0.00005170494,0.0005594433,0.0003021043,0.00002782023,0.0003809861,0.0001755359,0.0008679949,0.9558442,0.004598742,0.0002734803,0.03646033],"study_design_scores_gemma":[0.0000374267,0.000728082,0.0005153344,0.00002555447,0.00003567457,0.0006549583,0.00007256053,0.001092589,0.9823557,0.0009546342,0.01350414,0.00002327782],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9518019,0.01202002,0.02381868,0.0007071312,0.0001273149,0.0001358229,0.0001901655,0.0001269777,0.01107196],"genre_scores_gemma":[0.9697185,0.009330708,0.01690117,0.0001551125,0.00002372289,0.00004661598,0.0001681776,0.0000314801,0.003624606],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001168031,"threshold_uncertainty_score":0.004995823,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1651015354273368,"score_gpt":0.3159300685077272,"score_spread":0.1508285330803904,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}