{"id":"W2065931971","doi":"10.1016/j.carres.2008.08.025","title":"Application and limitations of the methyl imidate protection strategy of N-acetylglucosamine for glycosylations at O-4: synthesis of Lewis A and Lewis X trisaccharide analogues","year":2008,"lang":"en","type":"article","venue":"Carbohydrate Research","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":27,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Trisaccharide; N-Acetylglucosamine; Acceptor; Glycosylation; Residue (chemistry); Stereochemistry; Acetylglucosamine; Glucosamine; Monosaccharide; Disaccharide; Organic chemistry; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006812419,0.0001678996,0.0004008321,0.0001753124,0.000333793,0.00001356427,0.0002280742,0.0001849646,0.00001754762],"category_scores_gemma":[0.001552164,0.0001411376,0.0001350014,0.0006820965,0.0007994588,0.0001069112,0.0001458318,0.0002028579,5.089405e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008047648,"about_ca_system_score_gemma":0.0001476673,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003901538,"about_ca_topic_score_gemma":0.0001285814,"domain_scores_codex":[0.9982884,0.0001258698,0.0005470272,0.000367376,0.0003985018,0.0002728548],"domain_scores_gemma":[0.9963874,0.002068829,0.0003108012,0.0005171372,0.0006250071,0.00009087392],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001499,0.00009059332,0.0007700691,0.0006067389,0.0000981923,4.548724e-7,0.000412613,0.00009663879,0.9884745,0.0001814003,0.00001851411,0.009100398],"study_design_scores_gemma":[0.0003295419,0.00004098605,0.001393348,0.00008408767,0.00008390137,0.000008570354,0.0005147578,0.00429694,0.9923516,0.000604515,0.0001736714,0.0001181099],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971653,0.0006249166,0.000216316,0.0002543962,0.0000098881,0.0005121907,0.000316484,0.00001582081,0.0008846962],"genre_scores_gemma":[0.9975902,0.001324117,0.000200635,0.000001375295,0.00003851384,0.0005281011,0.00003447287,0.00002463121,0.0002579995],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008982288,"threshold_uncertainty_score":0.5755424,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1651015354273368,"score_gpt":0.3159300685077272,"score_spread":0.1508285330803904,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}