{"id":"W2065940966","doi":"10.1097/coc.0b013e3182568f7a","title":"Randomized Feasibility Study of De-escalated (Every 12 wk) Versus Standard (Every 3 to 4 wk) Intravenous Pamidronate in Women With Low-risk Bone Metastases From Breast Cancer","year":2012,"lang":"en","type":"article","venue":"American Journal of Clinical Oncology","topic":"Bone health and treatments","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; University of Toronto; Regional Municipality of Durham; University Health Network; St. Michael's Hospital; Ottawa Hospital; Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Randomized controlled trial; Breast cancer; Bone pain; Bisphosphonate; Surgery; N-terminal telopeptide; Confidence interval; Bone disease; Internal medicine; Cancer; Osteoporosis; Alkaline phosphatase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005997745,0.001125591,0.001932065,0.0005037779,0.0005209863,0.0008365099,0.001134846,0.001950369,0.004293097],"category_scores_gemma":[0.006521514,0.001003001,0.001115062,0.0003911531,0.001570043,0.001022809,0.0007312846,0.002212209,0.0007369712],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008148153,"about_ca_system_score_gemma":0.002336455,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006954319,"about_ca_topic_score_gemma":0.001125566,"domain_scores_codex":[0.9962363,0.002808381,0.0001892898,0.0003304218,0.0001697362,0.0002659022],"domain_scores_gemma":[0.9948832,0.002091047,0.001153511,0.0005080139,0.0003512856,0.001013035],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9514791,0.03548114,0.001853201,0.0001359935,0.0002349361,0.00003646538,0.00008394458,0.0002315851,0.002762128,0.00008173556,0.000156681,0.007463111],"study_design_scores_gemma":[0.6126223,0.3835597,0.002641006,0.00001071542,0.0001247606,0.00002453487,0.00003367894,0.0003061833,0.000283067,0.00007229772,0.0003123808,0.000009361996],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909019,0.0003235566,0.0005306019,0.0003117079,0.0002076064,0.007039195,0.0001566729,0.00002656571,0.0005021042],"genre_scores_gemma":[0.9876566,0.0002722233,0.002344762,0.0005567271,0.0002449121,0.008041203,0.0001888777,0.000008087315,0.0006866013],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005997745,"threshold_uncertainty_score":0.03171951,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05031585966688427,"score_gpt":0.4293842203283199,"score_spread":0.3790683606614356,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}