{"id":"W2065947481","doi":"10.1021/jo051560p","title":"Synthesis and Conformational Analysis of Bicyclic Sulfonium Salts. Structures Related to the Glycosidase Inhibitor Australine","year":2005,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"","keywords":"Sulfonium; Chemistry; Pyrrolizidine; Steric effects; Thioether; Stereochemistry; Intramolecular force; Vicinal; Bicyclic molecule; Glycoside hydrolase; Electrophile; Enzyme; Organic chemistry; Salt (chemistry); Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000113176,0.0003042279,0.0002551132,0.0001625985,0.0001376742,0.0002174132,0.0002606249,0.0002529559,0.0009498069],"category_scores_gemma":[0.0002056973,0.0001371526,0.0001183724,0.0002126541,0.000183218,0.0001660865,0.000138791,0.0003132358,0.000215835],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003338197,"about_ca_system_score_gemma":0.0002671092,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000694371,"about_ca_topic_score_gemma":0.001293165,"domain_scores_codex":[0.9999266,0.00001521643,0.000007096787,0.0000128943,0.00002106169,0.00001712396],"domain_scores_gemma":[0.9999142,0.00001086798,0.00002844531,0.000009483716,0.00001428118,0.00002269666],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002082277,0.00003502922,0.0001326334,0.00008240073,0.000009953344,0.0001240396,0.00005658552,0.0008358289,0.9920931,0.0003275004,0.00005189336,0.006042697],"study_design_scores_gemma":[0.0001065143,0.002065424,0.001150036,0.00001158299,0.00002679842,0.0002765219,0.00003062552,0.001339165,0.9900805,0.0001121005,0.004785913,0.00001476646],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916196,0.001568941,0.002643703,0.00008342432,0.00002507924,0.00009854633,0.0002709617,0.00004294594,0.003646731],"genre_scores_gemma":[0.9925431,0.001187878,0.003803424,0.00004365358,0.000007293521,0.00004207367,0.0004369549,0.00001564167,0.001919998],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009498069,"threshold_uncertainty_score":0.003177404,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007757773172155089,"score_gpt":0.228103250979331,"score_spread":0.2203454778071759,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}