{"id":"W2065948425","doi":"10.1038/bjc.2014.572","title":"The effects of CCR5 inhibition on regulatory T-cell recruitment to colorectal cancer","year":2014,"lang":"en","type":"article","venue":"British Journal of Cancer","topic":"Chemokine receptors and signaling","field":"Medicine","cited_by":92,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Bowel Disease Research Foundation; Medical Research Council; National Institute for Health and Care Research; Pfizer","keywords":"Colorectal cancer; Chemokine; Chemokine receptor; Infiltration (HVAC); Cancer research; Chemokine receptor CCR5; Immunology; Biology; Chemotaxis; Flow cytometry; Receptor; Cancer; Inflammation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002728652,0.0002119668,0.0002698149,0.0001295684,0.0001270824,0.0002859121,0.0002633435,0.0002548321,0.00200027],"category_scores_gemma":[0.0002440354,0.00008633253,0.0002164509,0.00008744877,0.0002060787,0.0001958033,0.0001200204,0.0007063081,0.000346004],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003423337,"about_ca_system_score_gemma":0.0002821134,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009587913,"about_ca_topic_score_gemma":0.00203563,"domain_scores_codex":[0.9998019,0.00005318685,0.00001542229,0.00001744637,0.00002924804,0.00008291549],"domain_scores_gemma":[0.9998628,0.0000393073,0.00002305584,0.00001555235,0.00001459645,0.0000447729],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004820082,0.0006877059,0.001132649,0.0003377367,0.00004554408,0.0001338692,0.00004896209,0.0005073607,0.9740184,0.0003724671,0.0007797442,0.01711555],"study_design_scores_gemma":[0.0004784524,0.01644217,0.01895942,0.00004128097,0.0001315171,0.0007215775,0.00008359575,0.00201497,0.9521914,0.00008571801,0.008832137,0.00001781419],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913269,0.005838949,0.0003828561,0.0001842859,0.00007957895,0.00003181733,0.0001482491,0.00003913666,0.001968302],"genre_scores_gemma":[0.9975767,0.001148433,0.0002693403,0.00008624335,0.00002338158,0.00001748743,0.000183362,0.000006132713,0.0006888978],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00200027,"threshold_uncertainty_score":0.006691575,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01055059270651797,"score_gpt":0.280351847018962,"score_spread":0.2698012543124441,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}