{"id":"W2065956856","doi":"10.1002/cbic.200800272","title":"Hydrophobic Interactions as Substitutes for a Conserved Disulfide Linkage in the Type IIa Bacteriocins, Leucocin A and Pediocin PA‐1","year":2008,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Probiotics and Fermented Foods","field":"Agricultural and Biological Sciences","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Disulfide bond; Chemistry; Bacteriocin; Stereochemistry; Disulfide Linkage; Hydrophobic effect; Amino acid; Non-covalent interactions; Biochemistry; Antimicrobial; Organic chemistry; Molecule; Cysteine; Hydrogen bond; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001508343,0.0002241924,0.0001414567,0.0001040393,0.0001280631,0.0002361068,0.0001612938,0.0002017182,0.0009483371],"category_scores_gemma":[0.0001648149,0.0001420262,0.0001271331,0.0001346534,0.0002205553,0.0001917832,0.0002401844,0.0003016211,0.0001923047],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002383544,"about_ca_system_score_gemma":0.0001336748,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002256768,"about_ca_topic_score_gemma":0.0003908007,"domain_scores_codex":[0.9998875,0.00004038992,0.000008817737,0.00001404097,0.00002404045,0.00002518783],"domain_scores_gemma":[0.9998904,0.00001990009,0.00003954056,0.000008143882,0.00000755782,0.00003446806],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004283319,0.00004990206,0.000254908,0.00004197357,0.000008043553,0.0001371202,0.00002112761,0.0003321379,0.996891,0.0003161122,0.0000232368,0.001496215],"study_design_scores_gemma":[0.00008955199,0.0007770305,0.001693894,0.000005145504,0.00002647641,0.0002988641,0.00003972091,0.0009193367,0.9942487,0.00005512988,0.001838987,0.000006999793],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986172,0.0001489085,0.0005472502,0.00001998131,0.000005339502,0.00001244339,0.00002713729,0.000008040724,0.0006137085],"genre_scores_gemma":[0.9983301,0.00009230339,0.000964816,0.00001707335,0.000002349823,0.000005882609,0.0000439048,0.000003855508,0.000539737],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009483371,"threshold_uncertainty_score":0.003172517,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0371234393775168,"score_gpt":0.2451851422558547,"score_spread":0.2080617028783379,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}