{"id":"W2065956856","doi":"10.1002/cbic.200800272","title":"Hydrophobic Interactions as Substitutes for a Conserved Disulfide Linkage in the Type IIa Bacteriocins, Leucocin A and Pediocin PA‐1","year":2008,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Probiotics and Fermented Foods","field":"Agricultural and Biological Sciences","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Disulfide bond; Chemistry; Bacteriocin; Stereochemistry; Disulfide Linkage; Hydrophobic effect; Amino acid; Non-covalent interactions; Biochemistry; Antimicrobial; Organic chemistry; Molecule; Cysteine; Hydrogen bond; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001408985,0.0001225495,0.000141688,0.00001028069,0.0002236141,0.00004530728,0.000178826,0.00007577829,0.00005234931],"category_scores_gemma":[0.00008107428,0.00004694053,0.00006206991,0.0002150514,0.0001063132,0.00006421335,0.00004879983,0.000136254,0.00001386432],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001914648,"about_ca_system_score_gemma":0.00001692643,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001660925,"about_ca_topic_score_gemma":0.0002545159,"domain_scores_codex":[0.999297,0.0000261829,0.0001651153,0.0002274552,0.00007460192,0.0002096119],"domain_scores_gemma":[0.9995914,0.0001952546,0.00005264627,0.00006658294,0.00003921028,0.00005497647],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006461141,0.0001395164,0.005914502,0.00001479311,0.00001467123,0.00001103942,0.0005912934,1.602263e-7,0.9909852,0.0001688474,0.001133891,0.000961485],"study_design_scores_gemma":[0.001105648,0.0007639491,0.2728859,0.0001029725,0.00004644466,0.0002147388,0.001655087,0.0002055368,0.6756244,0.0009851622,0.04587305,0.0005370489],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967748,0.0004276464,0.000001138091,0.001820489,0.00009003204,0.0002816634,0.00002208087,0.00002343708,0.0005587418],"genre_scores_gemma":[0.9983973,0.0002515317,0.00006427384,0.0004888344,0.0001286738,0.00003192479,0.0000996202,0.000001299425,0.0005365729],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3153607,"threshold_uncertainty_score":0.1914179,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0371234393775168,"score_gpt":0.2451851422558547,"score_spread":0.2080617028783379,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}