{"id":"W2065992040","doi":"10.1038/onc.2009.59","title":"Cyclooxygenase inhibitors differentially modulate p73 isoforms in neuroblastoma","year":2009,"lang":"en","type":"article","venue":"Oncogene","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Gene isoform; Downregulation and upregulation; Biology; Cancer research; Transactivation; Apoptosis; Neuroblastoma; E2F1; Cyclooxygenase; Isozyme; Cell biology; Cell culture; Transcription factor; Cell cycle; Gene; Enzyme; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007500322,0.0002338324,0.0003281374,0.0002845286,0.00006007827,0.00002702204,0.0001070478,0.00008312048,0.0001195646],"category_scores_gemma":[0.0000670209,0.0001830348,0.0001365295,0.0003709889,0.00003972706,0.0001072155,0.00004679392,0.0002404073,0.0002455165],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001148952,"about_ca_system_score_gemma":0.0001245968,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003218149,"about_ca_topic_score_gemma":0.00008434842,"domain_scores_codex":[0.9982598,0.0000450827,0.0003079215,0.0003995731,0.0004212386,0.0005663543],"domain_scores_gemma":[0.9991156,0.00002825491,0.00005372489,0.000376084,0.00004750243,0.0003788366],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001274234,0.002166056,0.006024676,0.00004976104,0.00006695966,0.004736099,0.0001029255,0.00004351019,0.8938065,0.0000651166,0.0009450311,0.09071916],"study_design_scores_gemma":[0.01090882,0.005192307,0.4951637,0.0002647817,0.00006972403,0.0004458181,0.00002012888,0.0007016927,0.4843442,0.000764114,0.001711408,0.0004133776],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950537,0.00009513625,0.00002418962,0.001191116,0.0001145418,0.0004632722,0.000008937106,0.00009328437,0.002955826],"genre_scores_gemma":[0.9973667,0.0001177985,0.0002256138,0.0006029085,0.00015384,0.0000159832,0.00003025751,0.00003024378,0.001456668],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.489139,"threshold_uncertainty_score":0.7463942,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01171841708265204,"score_gpt":0.2795066155786681,"score_spread":0.267788198496016,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}