{"id":"W2066116844","doi":"10.1093/nar/gki292","title":"Translation of the F protein of hepatitis C virus is initiated at a non-AUG codon in a +1 reading frame relative to the polyprotein","year":2005,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"Hepatitis C virus research","field":"Medicine","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Frameshift mutation; Open reading frame; Biology; Reading frame; Coding region; Internal ribosome entry site; Stop codon; Start codon; Molecular biology; Genetics; Eukaryotic translation; Luciferase; Shine-Dalgarno sequence; Translation (biology); Ribosome; Messenger RNA; Gene; Peptide sequence; RNA; Transfection; Mutation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004264836,0.0005120492,0.0004560591,0.0003121494,0.0002527073,0.0004306542,0.0001761393,0.0004882323,0.0007451866],"category_scores_gemma":[0.0003434303,0.0002211799,0.0003605009,0.0001737528,0.0003325126,0.0003132214,0.0001924424,0.0004646394,0.0004448568],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006121711,"about_ca_system_score_gemma":0.0003649592,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009000059,"about_ca_topic_score_gemma":0.000826844,"domain_scores_codex":[0.9996277,0.00007420925,0.0000254172,0.000102408,0.0001125668,0.00005769604],"domain_scores_gemma":[0.9997869,0.00005679877,0.00006977646,0.0000225672,0.00003320391,0.00003072524],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000106768,0.00004768448,0.0006596335,0.00004758354,0.000003796142,0.00003820489,0.00002051201,0.00007848193,0.9967231,0.0001396196,0.0000361659,0.002098384],"study_design_scores_gemma":[0.00001672739,0.0005250289,0.006348144,0.00001529028,0.00001040558,0.0002953479,0.00001866186,0.001049905,0.9895493,0.00006111069,0.002098591,0.00001149293],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926549,0.001244801,0.004603933,0.00005577999,0.00003969508,0.00004392529,0.0002245801,0.00007881054,0.001053681],"genre_scores_gemma":[0.9775718,0.001259447,0.01612904,0.00007670413,0.00003226174,0.00006054963,0.001238634,0.00003150232,0.00360007],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009000059,"threshold_uncertainty_score":0.004441619,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09261244493232912,"score_gpt":0.3885150373046148,"score_spread":0.2959025923722857,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}