{"id":"W2066145073","doi":"10.1016/j.amjsurg.2006.02.005","title":"Derangement of the E-cadherin/catenin complex is involved in transformation of differentiated to anaplastic thyroid carcinoma","year":2006,"lang":"en","type":"article","venue":"The American Journal of Surgery","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":false,"ca_institutions":"Vancouver General Hospital; University of British Columbia; BC Cancer Agency; St. Paul's Hospital","funders":"","keywords":"Anaplastic thyroid cancer; Anaplastic carcinoma; Immunohistochemistry; Cadherin; Pathology; Thyroid carcinoma; Thyroid; Cancer research; Thyroid cancer; Malignant transformation; Catenin; Medicine; Carcinoma; Internal medicine; Biology; Cell; Wnt signaling pathway; Signal transduction; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001138308,0.0001615794,0.0001540239,0.0006023739,0.000252306,0.000449218,0.0001502857,0.0001958352,0.001312279],"category_scores_gemma":[0.0002226723,0.0001675414,0.0001769775,0.0003178319,0.0002453798,0.00017549,0.0002034066,0.0003093834,0.0002838647],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005081604,"about_ca_system_score_gemma":0.0003537498,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001897768,"about_ca_topic_score_gemma":0.001694801,"domain_scores_codex":[0.9998884,0.00001295823,0.00001244482,0.00001279493,0.00004281429,0.00003061393],"domain_scores_gemma":[0.9998789,0.00001656416,0.00002408237,0.00001471461,0.00002070194,0.00004499802],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003105905,0.00003996385,0.009829105,0.00002779375,0.0000118693,0.0008796329,0.00005226584,0.00006828456,0.9864161,0.0002657802,0.00006536215,0.002033343],"study_design_scores_gemma":[0.00006700588,0.0003180885,0.3788885,0.000006200882,0.00008843173,0.005080232,0.0003655947,0.002039182,0.6077425,0.0004633591,0.004924775,0.00001596059],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984503,0.000587587,0.0002371257,0.00003698993,0.000006374994,0.000007074378,0.00004954116,0.00001783147,0.000607116],"genre_scores_gemma":[0.9990785,0.0001827481,0.00008311737,0.000008830041,0.000002272158,0.000003100118,0.00007922392,0.000002265812,0.0005598784],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001897768,"threshold_uncertainty_score":0.004390061,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02241288146915899,"score_gpt":0.2329082772892391,"score_spread":0.2104953958200801,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}