{"id":"W2066171956","doi":"10.1021/bi100036f","title":"Circular Permutation of <i>Bacillus circulans</i> Xylanase: A Kinetic and Structural Study","year":2010,"lang":"en","type":"article","venue":"Biochemistry","topic":"Biofuel production and bioconversion","field":"Engineering","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Bacillus circulans; Xylanase; Chemistry; Bacillus (shape); Microbiology; Biochemistry; Biology; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001833692,0.000278842,0.0001895274,0.0001100657,0.0001284342,0.0002912109,0.0002393414,0.0002070154,0.0004673642],"category_scores_gemma":[0.0003788786,0.0001450426,0.0001751372,0.0002470109,0.00019361,0.0002730982,0.0001187098,0.0004660788,0.0002007527],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003597018,"about_ca_system_score_gemma":0.0001938627,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001833701,"about_ca_topic_score_gemma":0.00111917,"domain_scores_codex":[0.9998701,0.00002059357,0.000008007526,0.0000330535,0.00004197657,0.00002628882],"domain_scores_gemma":[0.9998185,0.00004424789,0.00004968642,0.00001637431,0.00003865838,0.00003252684],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001364495,0.00007823583,0.0007121949,0.00005283614,0.00001204588,0.00005615165,0.00005155424,0.00116179,0.9939569,0.0002127827,0.00007991352,0.003489073],"study_design_scores_gemma":[0.000009868021,0.000326732,0.003743922,0.000005384495,0.0000147793,0.0002363339,0.00004464894,0.009941308,0.9837087,0.00006757958,0.001883394,0.00001729472],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995474,0.0007905,0.002634831,0.0000523167,0.000009916453,0.00001405975,0.000119482,0.00002894848,0.0008758078],"genre_scores_gemma":[0.9935051,0.0008485402,0.003752546,0.00002421654,0.000007169866,0.000009204762,0.0006407559,0.00003615738,0.001176206],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001833701,"threshold_uncertainty_score":0.003646016,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004771666666324648,"score_gpt":0.1974439653992152,"score_spread":0.1926722987328905,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}