{"id":"W2066190379","doi":"10.1053/j.seminhematol.2008.03.003","title":"On-Label Versus Off-Label Use of Recombinant Activated Factor VII: A Comprehensive Review of Use in Two Canadian Centers","year":2008,"lang":"en","type":"review","venue":"Seminars in Hematology","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hamilton Health Sciences; Hospital for Sick Children; McMaster University; University of Toronto","funders":"","keywords":"Medicine; Off-label use; Recombinant factor VIIa; Factor VIIa; Population; Intensive care medicine; Surgery; Pharmacology; Internal medicine; Environmental health; Tissue factor; Coagulation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002196596,0.0007017058,0.002453913,0.004237394,0.0004737568,0.001425818,0.001278671,0.0008160279,0.002155257],"category_scores_gemma":[0.003447994,0.0002873446,0.001306578,0.007736051,0.0007106276,0.000694113,0.0004664697,0.0008718902,0.0002235091],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005779334,"about_ca_system_score_gemma":0.01510926,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.1246825,"about_ca_topic_score_gemma":0.305945,"domain_scores_codex":[0.9989686,0.0001515944,0.0001786769,0.0001233018,0.0005029288,0.00007493788],"domain_scores_gemma":[0.9969388,0.0012602,0.0006406714,0.00003922029,0.0009536732,0.0001673348],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006581194,0.00007376006,0.002482003,0.06007997,0.0008250606,0.0002400773,0.000321208,0.000208043,0.00105462,0.000564434,0.015602,0.9178907],"study_design_scores_gemma":[0.0005135764,0.0008507387,0.05151343,0.09776899,0.01112931,0.003017866,0.001184132,0.0002258989,0.002116555,0.0004560974,0.8310359,0.0001874573],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0006737549,0.9984145,0.00002845711,0.0001845575,0.0000307063,0.00001187359,0.00009828997,0.000002782237,0.0005550238],"genre_scores_gemma":[0.002657188,0.9968216,0.0001446449,0.0001740309,0.00001691637,0.000004940875,0.00006694793,0.0000014447,0.0001121351],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8753175,"threshold_uncertainty_score":0.2479135,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1948777253795904,"score_gpt":0.4220467767651181,"score_spread":0.2271690513855278,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}