{"id":"W2066203052","doi":"10.1074/jbc.m606197200","title":"Differential Modulation of 3T3-L1 Adipogenesis Mediated by 11β-Hydroxysteroid Dehydrogenase-1 Levels","year":2007,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Hormonal Regulation and Hypertension","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute","keywords":"Adipogenesis; Glucocorticoid; 3T3-L1; 11β-hydroxysteroid dehydrogenase type 1; Glucocorticoid receptor; 3T3 cells; Endocrinology; Internal medicine; Dehydrogenase; Cell biology; Cellular differentiation; Biology; Chemistry; Cell culture; Enzyme; Biochemistry; Adipose tissue; Transfection; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003115599,0.0001349769,0.000451216,0.00004720374,0.00002649587,0.000004899328,0.00008930223,0.000283073,0.0005323983],"category_scores_gemma":[0.0003222453,0.00008634205,0.0002169049,0.0001220359,0.00008878532,0.00003631506,0.00002336066,0.0001919561,0.000004162943],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006503862,"about_ca_system_score_gemma":0.00004673025,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001772152,"about_ca_topic_score_gemma":2.014684e-7,"domain_scores_codex":[0.9985823,0.00002365296,0.0007108517,0.0001296768,0.0003744862,0.0001790338],"domain_scores_gemma":[0.9987953,0.0001236726,0.0004359157,0.0001116015,0.0002852904,0.0002481832],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005232589,0.0002010399,0.007773194,0.00002919796,0.0000827592,0.00005583024,0.00001261598,0.000004711079,0.9883881,0.000001560965,0.0002226162,0.002705084],"study_design_scores_gemma":[0.001264378,0.0002436055,0.1255208,0.00006180137,0.00006867028,0.0003835779,0.00002605137,0.0003788834,0.8708155,0.00002720895,0.001123122,0.00008641897],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974428,0.0006569698,0.001256297,0.0002189887,0.00005163005,0.00006078991,0.00001666557,0.00001205412,0.0002838042],"genre_scores_gemma":[0.9991548,0.0000755618,0.0002430653,0.000101658,0.0002385261,3.886227e-7,0.00004946484,0.000008872224,0.0001276477],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1177476,"threshold_uncertainty_score":0.5829388,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03720206472121203,"score_gpt":0.2735843326174082,"score_spread":0.2363822678961962,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}