{"id":"W2066230066","doi":"10.1016/j.neuropharm.2012.05.033","title":"Inhibition of human astrocyte and microglia neurotoxicity by calcium channel blockers","year":2012,"lang":"en","type":"article","venue":"Neuropharmacology","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":67,"is_retracted":false,"has_abstract":false,"ca_institutions":"Okanagan University College; University of British Columbia, Okanagan Campus; University of British Columbia","funders":"Fondation pour la Recherche sur Alzheimer","keywords":"Microglia; Neurotoxicity; Calcium channel; Astrocyte; Pharmacology; Neuroinflammation; Verapamil; Chemistry; Biology; Cell biology; Medicine; Neuroscience; Inflammation; Calcium; Immunology; Toxicity; Internal medicine; Central nervous system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000127347,0.0002049024,0.0002186323,0.0001458519,0.0002119042,0.0000201743,0.000126613,0.00007252574,0.0001604953],"category_scores_gemma":[0.0001095974,0.0002173633,0.00005275964,0.0002010966,0.0001814184,0.0002520988,0.0001170847,0.0002635171,0.00004026136],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000126348,"about_ca_system_score_gemma":0.00001331751,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002597064,"about_ca_topic_score_gemma":2.814342e-7,"domain_scores_codex":[0.9981303,0.0004797247,0.0003675659,0.0004038224,0.0002068982,0.0004117084],"domain_scores_gemma":[0.9992153,0.00014616,0.0002187537,0.0001582893,0.00003626859,0.000225232],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004872175,0.0001372933,0.00009981555,0.00001874423,0.000001672587,0.00001456014,0.00009043753,0.000004016886,0.9963142,0.0005599425,0.002631492,0.00007906386],"study_design_scores_gemma":[0.0009000239,0.0002742396,0.0002774511,0.000002243574,0.00001782064,0.00008041534,0.000006869302,0.0002071429,0.9960533,0.0000231514,0.002014437,0.0001428695],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977871,0.0000244941,0.000164463,0.0005051755,0.000720625,0.0004082014,0.00004174535,0.0001144194,0.0002338234],"genre_scores_gemma":[0.9945853,0.00004722591,0.00003757302,0.004813548,0.0001520517,0.0000330832,0.000004783699,0.00003483987,0.0002915436],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004308373,"threshold_uncertainty_score":0.8863817,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04061683986119124,"score_gpt":0.3045487579952909,"score_spread":0.2639319181340996,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}