{"id":"W2066250353","doi":"10.3389/fgene.2015.00161","title":"Transcriptional control of stem cell fate by E2Fs and pocket proteins","year":2015,"lang":"en","type":"review","venue":"Frontiers in Genetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Ottawa Hospital","funders":"Canadian Institutes of Health Research","keywords":"Biology; Cell fate determination; Embryonic stem cell; Stem cell; Epigenetics; E2F; Induced pluripotent stem cell; Transcription factor; Cell biology; Cellular differentiation; Genetics; Regeneration (biology); Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006454966,0.0006839047,0.0008091592,0.001401651,0.0002419535,0.0006550589,0.0007989575,0.0009870543,0.0026704],"category_scores_gemma":[0.0006348587,0.0002763957,0.0002435436,0.001342813,0.0006556548,0.001353319,0.0007685522,0.00124763,0.0018748],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007243845,"about_ca_system_score_gemma":0.0007386503,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00069844,"about_ca_topic_score_gemma":0.00136033,"domain_scores_codex":[0.9998672,0.00001960693,0.00002003215,0.00003283987,0.00004347565,0.000016841],"domain_scores_gemma":[0.9997571,0.0001126969,0.00003375388,0.000009980397,0.00005673926,0.00002975405],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000598922,0.00002727538,0.0002013898,0.007135889,0.00004632968,0.000220835,0.00005491286,0.000409373,0.003308193,0.009255069,0.0191489,0.9601319],"study_design_scores_gemma":[0.000006145162,0.00002795467,0.0005442371,0.0006879493,0.0000225418,0.0007075869,0.00003507175,0.00004858449,0.0008608581,0.001730988,0.9953181,0.000009899801],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002082459,0.9975097,0.000233519,0.0003319864,0.0001930853,0.000003084883,0.00002022957,0.00000878793,0.001491331],"genre_scores_gemma":[0.001355482,0.9967654,0.0002802798,0.0002191739,0.0001264183,0.000005202002,0.00003421652,0.00000238521,0.001211335],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0026704,"threshold_uncertainty_score":0.008933425,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01905076114976002,"score_gpt":0.2648654350698481,"score_spread":0.245814673920088,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}