{"id":"W2066325099","doi":"10.1016/s0008-6363(03)00390-0","title":"Tetrahydrobiopterin and antioxidants reverse the coronary endothelial dysfunction associated with left ventricular hypertrophy in a porcine model","year":2003,"lang":"en","type":"article","venue":"Cardiovascular Research","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"","keywords":"Internal medicine; Left ventricular hypertrophy; Superoxide dismutase; Endothelial dysfunction; Medicine; Cardiology; Endothelium; Endocrinology; Muscle hypertrophy; Coronary arteries; Ventricular hypertrophy; Nitric oxide synthase; Nitric oxide; Oxidative stress; Blood pressure; Artery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003266382,0.0001887259,0.0004817409,0.00030875,0.0001792594,0.00003126898,0.00009896967,0.0001315252,0.00002631483],"category_scores_gemma":[0.0008238568,0.0001209055,0.0002480337,0.0006734397,0.0002232563,0.00009133468,0.00005246943,0.0006605539,0.00002157136],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001971396,"about_ca_system_score_gemma":0.0001744423,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001304177,"about_ca_topic_score_gemma":0.00001387689,"domain_scores_codex":[0.997038,0.0007449946,0.0002069008,0.0004465717,0.001000939,0.000562589],"domain_scores_gemma":[0.9987791,0.0002053467,0.00002811815,0.0006303966,0.0002077516,0.000149346],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.007465059,0.003475732,0.6360634,0.001572733,0.01515699,0.0515595,0.002154928,0.03637936,0.2008301,0.001097074,0.004605677,0.03963948],"study_design_scores_gemma":[0.09855678,0.006534562,0.6933473,0.003426855,0.003636996,0.02467426,0.002830243,0.05566659,0.05382217,0.001400875,0.05348346,0.002619887],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920899,0.00445158,0.0005052387,0.0001596032,0.00005428094,0.001046942,0.000007728066,0.00003566507,0.001649091],"genre_scores_gemma":[0.9980844,0.0007283614,0.0001790243,0.0001014524,0.0000613985,0.00004854216,0.00001307406,0.00004298904,0.0007407573],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1470079,"threshold_uncertainty_score":0.4930384,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0394788556596747,"score_gpt":0.2773978817277139,"score_spread":0.2379190260680392,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}