{"id":"W2066427082","doi":"10.1007/s00125-011-2072-1","title":"Per-arnt-sim (PAS) domain kinase (PASK) as a regulator of glucagon secretion","year":2011,"lang":"en","type":"letter","venue":"Diabetologia","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Alberta Innovates; Canadian Diabetes Association","keywords":"Glucagon; Endocrinology; Secretion; Internal medicine; Regulator; Paracrine signalling; Mechanism (biology); Type 2 diabetes; Alpha cell; Diabetes mellitus; PAS domain; Biology; Cell biology; Islet; Medicine; Beta cell; Receptor; Insulin; Biochemistry; Transcription factor; Physics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005856647,0.0006620437,0.0008826963,0.0003254982,0.0008579938,0.001668522,0.0006083052,0.01263276,0.001975354],"category_scores_gemma":[0.004449057,0.0003278311,0.0008095542,0.0002609564,0.001180216,0.001617782,0.0005620857,0.01128658,0.00174635],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00180921,"about_ca_system_score_gemma":0.0005272801,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003638137,"about_ca_topic_score_gemma":0.0005161975,"domain_scores_codex":[0.9994977,0.0001633722,0.0000704276,0.00006580073,0.0001276491,0.00007511584],"domain_scores_gemma":[0.9992268,0.0004624049,0.00007336368,0.0000366509,0.00007368432,0.0001270261],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001425477,0.0002968906,0.006477007,0.0003890335,0.0001702551,0.1886882,0.0002694192,0.0009791836,0.005869213,0.01686403,0.7002668,0.07830446],"study_design_scores_gemma":[0.001688461,0.000741601,0.007157602,0.0003653258,0.0002457777,0.1877545,0.0004596669,0.006015636,0.004840698,0.03190369,0.7586926,0.0001344351],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.01851338,0.02087679,0.0009773616,0.8886237,0.05597986,0.00003064506,0.00007510393,0.0001022559,0.01482095],"genre_scores_gemma":[0.2599879,0.02127423,0.001710077,0.3928056,0.3019029,0.0001058514,0.0001117472,0.00004710426,0.02205462],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01263276,"threshold_uncertainty_score":0.01312679,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02244116170672698,"score_gpt":0.2427262532422042,"score_spread":0.2202850915354772,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}