{"id":"W2066488419","doi":"10.1002/pro.649","title":"Structural and enzymatic characterization of NanS (YjhS), a 9‐<i>O</i>‐Acetyl <i>N</i>‐acetylneuraminic acid esterase from <i>Escherichia coli O157:H7</i>","year":2011,"lang":"en","type":"article","venue":"Protein Science","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; National Research Council Canada; Biotechnology Research Institute; Institute for Biological Sciences; McGill University","funders":"Basic Energy Sciences; National Research Council Canada; National Center for Research Resources; Western Economic Diversification Canada; Biological and Environmental Research; Natural Sciences and Engineering Research Council of Canada; Brookhaven National Laboratory; Canadian Institutes of Health Research; National Institutes of Health; Canadian Light Source; U.S. Department of Energy","keywords":"Esterase; Sialic acid; Enzyme; Biochemistry; Chemistry; Neuraminidase; Hydrolase; Escherichia coli; Stereochemistry; Biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002041247,0.0002717108,0.0001853337,0.0001704542,0.0001529597,0.0002207105,0.0002521564,0.0001773202,0.000510042],"category_scores_gemma":[0.0002579024,0.0001074248,0.0002683986,0.0003565617,0.0002322486,0.0001929446,0.0001513148,0.000384072,0.0002765742],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003870835,"about_ca_system_score_gemma":0.0004862445,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003762027,"about_ca_topic_score_gemma":0.003080492,"domain_scores_codex":[0.9999171,0.00001001396,0.000006065343,0.00001162253,0.0000377695,0.00001737758],"domain_scores_gemma":[0.999849,0.00001391611,0.00004318271,0.00001162748,0.0000346633,0.00004765681],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000164051,0.00008454854,0.002414403,0.00006363438,0.00001057166,0.000173677,0.00008590768,0.0005648594,0.991286,0.0002542102,0.000151819,0.004746501],"study_design_scores_gemma":[0.00004804596,0.0009544436,0.08879552,0.00001919994,0.00006107621,0.001385765,0.0004028964,0.006322539,0.8796167,0.0002896752,0.02207732,0.00002694437],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959908,0.0008625398,0.001258235,0.00011754,0.00001506083,0.0000216802,0.0007107941,0.00001382671,0.001009507],"genre_scores_gemma":[0.9802936,0.001663256,0.004977773,0.00007776176,0.00002135593,0.00002308841,0.009372009,0.00002879752,0.00354225],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003762027,"threshold_uncertainty_score":0.007480264,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02223139107058805,"score_gpt":0.2534102295215459,"score_spread":0.2311788384509579,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}