{"id":"W2066564704","doi":"10.1038/nature14266","title":"Pugh et al. reply","year":2015,"lang":"en","type":"letter","venue":"Nature","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba; University Health Network; University of Toronto; Princess Margaret Cancer Centre","funders":"","keywords":"Computational biology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004172808,0.0007422458,0.001482344,0.0008374287,0.0039375,0.004371658,0.002548044,0.04086062,0.009683591],"category_scores_gemma":[0.02501462,0.0008568395,0.001171023,0.0005908301,0.003592334,0.004385995,0.002299818,0.04270791,0.007472563],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002423,"about_ca_system_score_gemma":0.00336812,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004246512,"about_ca_topic_score_gemma":0.005940323,"domain_scores_codex":[0.9975396,0.0007047415,0.0001983649,0.0004025338,0.0008057742,0.0003489242],"domain_scores_gemma":[0.9939473,0.003101334,0.0003167149,0.0002540927,0.00130888,0.001071609],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003175928,0.00001333744,0.0001794148,0.00001768969,0.000007785729,0.0003405096,0.00005287338,0.00002154596,0.00005107689,0.001059752,0.9952685,0.002955689],"study_design_scores_gemma":[0.0001303903,0.00006219478,0.0008149394,0.0001844641,0.00003619423,0.00120869,0.0004655139,0.0003113306,0.0003802974,0.01405551,0.9822546,0.00009588062],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0002035371,0.001247686,0.00008797298,0.9726706,0.02403169,0.000009597962,0.00005736058,0.00004508828,0.001646487],"genre_scores_gemma":[0.002329563,0.0007693763,0.0001061596,0.976188,0.0160406,0.00002961341,0.00002760574,0.00002121443,0.004487878],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.04086062,"threshold_uncertainty_score":0.03239483,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007844179446248222,"score_gpt":0.2653680082248289,"score_spread":0.2575238287785807,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}