{"id":"W2066615572","doi":"10.1111/pcmr.12067","title":"<scp>PMEL</scp>: a pigment cell‐specific model for functional amyloid formation","year":2013,"lang":"en","type":"review","venue":"Pigment Cell & Melanoma Research","topic":"melanin and skin pigmentation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":187,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of General Medical Sciences; Centre National de la Recherche Scientifique; National Eye Institute; Institut national de la recherche scientifique; National Institutes of Health; National Science Foundation","keywords":"Melanosome; Cell biology; Endoplasmic reticulum; Biology; Amyloid (mycology); Endosome; Organelle; Genetics; Intracellular; Melanin","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002820246,0.0007272703,0.0005695859,0.001606105,0.0003045869,0.0006914196,0.0007048193,0.001058342,0.003222948],"category_scores_gemma":[0.0002338217,0.0001660396,0.0003721824,0.00132963,0.0006668749,0.001459826,0.0005997713,0.001671345,0.00289693],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008118218,"about_ca_system_score_gemma":0.0006656125,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008309378,"about_ca_topic_score_gemma":0.001077506,"domain_scores_codex":[0.999923,0.00001257105,0.000008356113,0.00001662823,0.00003086964,0.000008622828],"domain_scores_gemma":[0.9999212,0.00002675727,0.00001182489,0.000004697639,0.00002357032,0.00001187888],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007365854,0.00006974682,0.0002399202,0.01112243,0.00005599415,0.0005851001,0.0001403085,0.0007714878,0.01540527,0.05914994,0.07287636,0.8395097],"study_design_scores_gemma":[0.000004257687,0.00003106182,0.0002587257,0.0007509952,0.00001447595,0.00109288,0.00003275976,0.0001041972,0.0009160201,0.004656461,0.9921278,0.00001032189],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000495709,0.9861112,0.001255111,0.0009548208,0.0007434848,0.00001240931,0.00005108417,0.00004235588,0.01033374],"genre_scores_gemma":[0.002646123,0.990892,0.0008941335,0.0004977455,0.0002303387,0.0000188147,0.00008721387,0.00000828438,0.004725394],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003222948,"threshold_uncertainty_score":0.01078182,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.152049658878377,"score_gpt":0.3675033418510045,"score_spread":0.2154536829726275,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}