{"id":"W2066632508","doi":"10.1128/aac.45.5.1561-1564.2001","title":"Pharmacokinetics of Itraconazole Oral Solution in Neutropenic Children during Long-Term Prophylaxis","year":2001,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotel Dieu Hospital","funders":"","keywords":"Itraconazole; Pharmacokinetics; Medicine; Plasma concentration; Neutropenia; Pharmacology; Oral administration; Internal medicine; Chemotherapy; Antifungal; Dermatology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003124272,0.0001870486,0.0007028627,0.0001950642,0.0001868194,0.0003880567,0.0001120826,0.0002729034,0.0004246755],"category_scores_gemma":[0.002199788,0.0001252684,0.0001963305,0.0002904163,0.0003055062,0.0003583827,0.0001444603,0.0004944418,0.00007910236],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003275087,"about_ca_system_score_gemma":0.0003321366,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008872341,"about_ca_topic_score_gemma":0.0006863317,"domain_scores_codex":[0.9997472,0.000084516,0.00001525045,0.00003133513,0.00006507594,0.00005662378],"domain_scores_gemma":[0.9991924,0.0002528047,0.0002836386,0.00004358275,0.0000663695,0.0001612437],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.05465325,0.00192058,0.5720669,0.0005426537,0.0004923974,0.002714508,0.00200657,0.002722467,0.1884373,0.0005324665,0.0009011799,0.1730097],"study_design_scores_gemma":[0.001431988,0.09478121,0.8446687,0.00007720498,0.0005884128,0.006476558,0.0009054045,0.002320405,0.0431127,0.000212549,0.005360542,0.00006425298],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988512,0.0008853264,0.0001099062,0.00001857136,0.00000356941,0.000007383515,0.00002664592,0.000003868093,0.00009350214],"genre_scores_gemma":[0.9991948,0.0003733612,0.0001951561,0.00003245637,0.00001062683,0.00001320215,0.00009580538,0.00000258015,0.00008203207],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008872341,"threshold_uncertainty_score":0.002376258,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01441244665858227,"score_gpt":0.2844994592309851,"score_spread":0.2700870125724028,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}