{"id":"W2066719210","doi":"10.1038/ni.2023","title":"An unexpected role for MHC class II","year":2011,"lang":"en","type":"letter","venue":"Nature Immunology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hôpital Saint-Luc; Centre Hospitalier de l’Université de Montréal","funders":"","keywords":"Major histocompatibility complex; Cell biology; MHC class II; MHC class I; CD74; Biology; Signal transduction; Function (biology); Antigen presentation; CD8; Intracellular; Antigen processing; Immunology; Antigen; T cell; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000942141,0.0004808717,0.000535216,0.0001964425,0.001004731,0.00164708,0.0007578474,0.00707464,0.002730594],"category_scores_gemma":[0.002520113,0.0002057687,0.0003432159,0.0001431162,0.001593154,0.001408545,0.0008242956,0.01075517,0.001387307],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008796678,"about_ca_system_score_gemma":0.0004845448,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002604041,"about_ca_topic_score_gemma":0.0004563509,"domain_scores_codex":[0.9996475,0.00007750414,0.00002514464,0.00006168758,0.0001123817,0.0000758047],"domain_scores_gemma":[0.9989525,0.00060896,0.00005071718,0.00009881412,0.0001320403,0.0001569341],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001147696,0.0001000339,0.00127887,0.0004662299,0.00005013534,0.0162949,0.0002187709,0.0002164539,0.02036872,0.02893611,0.8670397,0.06388238],"study_design_scores_gemma":[0.0003252416,0.0001774095,0.00160384,0.0001116007,0.00006104004,0.01053279,0.0002303857,0.001294663,0.008725085,0.02830777,0.9485803,0.00004988855],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.01224796,0.02354326,0.002299383,0.8581158,0.08605245,0.0000300957,0.0001376239,0.0003024979,0.01727091],"genre_scores_gemma":[0.2079987,0.02382361,0.004278291,0.5684872,0.1536816,0.0001560547,0.0002137415,0.0001142462,0.04124655],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.00707464,"threshold_uncertainty_score":0.009134769,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006534628546297705,"score_gpt":0.2353946527321914,"score_spread":0.2288600241858937,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}