{"id":"W2066719894","doi":"10.6000/1929-2279.2012.01.02.2","title":"A Review on EZH2 and its Epigenetic Association with Breast Cancer","year":2012,"lang":"en","type":"review","venue":"Journal of cancer research updates","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"PRC2; EZH2; Biology; Cancer research; Gene silencing; Breast cancer; Epigenetics; Histone H3; Histone methyltransferase; Cancer; Histone; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002628393,0.0002626941,0.0008440149,0.0001924977,0.0001104434,0.00005522355,0.000274342,0.0002728704,0.0001107281],"category_scores_gemma":[0.0002014616,0.0001692702,0.0001881982,0.0002868493,0.00004299872,0.00001093479,0.00009160285,0.000758255,0.000008065213],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002518919,"about_ca_system_score_gemma":0.0008468255,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000294983,"about_ca_topic_score_gemma":0.00006087205,"domain_scores_codex":[0.9973128,0.0007130094,0.000562289,0.0002670127,0.000722594,0.0004223162],"domain_scores_gemma":[0.9974415,0.0001266709,0.0008868504,0.0002176637,0.001101003,0.0002263481],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007477781,0.00006849005,0.0005237847,0.0152366,0.0006647339,0.000004504108,0.00001141426,0.000005690455,0.0006118885,0.000008222249,0.003409903,0.97938],"study_design_scores_gemma":[0.0002025534,0.0003570311,0.0001756132,0.02783603,0.0006034399,0.00002361387,0.000002853652,4.87255e-7,0.001100738,0.00001011469,0.9694912,0.0001963311],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007910889,0.997807,0.000003619094,0.0005507912,0.0001509857,0.0004717453,0.000141597,0.000001665809,0.00008149518],"genre_scores_gemma":[0.0006629851,0.9973959,0.00002788961,0.00009454524,0.001247987,0.00009686477,0.000036389,0.00005256437,0.000384927],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9791837,"threshold_uncertainty_score":0.6902638,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0853358334681937,"score_gpt":0.4512101551325877,"score_spread":0.3658743216643939,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}