{"id":"W2066719894","doi":"10.6000/1929-2279.2012.01.02.2","title":"A Review on EZH2 and its Epigenetic Association with Breast Cancer","year":2012,"lang":"en","type":"review","venue":"Journal of cancer research updates","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"PRC2; EZH2; Biology; Cancer research; Gene silencing; Breast cancer; Epigenetics; Histone H3; Histone methyltransferase; Cancer; Histone; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003216778,0.0005748977,0.0008272956,0.002374737,0.000224257,0.0007202516,0.0005456499,0.0007425538,0.006630156],"category_scores_gemma":[0.0006398647,0.0002109442,0.0004927825,0.003104778,0.0002314021,0.001016026,0.0004999361,0.0009509234,0.001947143],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004590293,"about_ca_system_score_gemma":0.0007000053,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007738877,"about_ca_topic_score_gemma":0.001260564,"domain_scores_codex":[0.9998475,0.00002943341,0.00002991492,0.00003689542,0.00004166045,0.00001443629],"domain_scores_gemma":[0.9996704,0.0001515479,0.00005910611,0.000009356048,0.00007274371,0.00003694898],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002013571,0.00007624135,0.0008509001,0.02286324,0.0001923301,0.0007210131,0.0001276118,0.0003252774,0.005683261,0.002240635,0.115754,0.850964],"study_design_scores_gemma":[0.000008279111,0.00008280361,0.001856578,0.001992016,0.0001585528,0.002217358,0.00004180047,0.00005821031,0.0005608651,0.0006052233,0.992403,0.00001537432],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002366027,0.9975069,0.0001528197,0.0004674391,0.0005881337,0.000003257,0.00004678502,0.00000953306,0.0009886436],"genre_scores_gemma":[0.001050061,0.9956564,0.0002252712,0.000507126,0.001059223,0.000007329471,0.0001440669,0.00000371889,0.001346781],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.006630156,"threshold_uncertainty_score":0.02218008,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0853358334681937,"score_gpt":0.4512101551325877,"score_spread":0.3658743216643939,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}